Lixisenatide requires a functional gut-vagus nerve-brain axis to trigger insulin secretion in controls and type 2 diabetic mice - Charpentier, Julie; Waget, Aurélie; Klopp, Pascale; Magnan, Christophe; Cruciani-Guglielmacci, Céline; Lee, Shin Jae; Burcelin, Rémy; Grasset, Estelle (American journal of physiology: Gastrointestinal and liver physiology, 2018)
Keywords: Animal models; Blood glucose; Brain stem; c-Fos protein; Diabetes; Diabetes mellitus; Firing rate; Gastric emptying; Glucagon; Glucagon-like peptide 1; Glucose; High fat diet; Insulin; Insulin resistance; Insulin secretion; Laboratory animals; Life Sciences; Secretion; Solitary tract nucleus; Vagus nerve; vagus nerve; autonomic nervous system; GLP-1 receptor agonist; GLP-1 analogs; incretin; PEPTIDE-1 RECEPTOR; CELLS; ACTIVATION; TRUNCALLY VAGOTOMIZED SUBJECTS; FOOD-INTAKE; GLUCOSE; INCREASES; GLP-1 RECEPTOR AGONIST; SENSOR; EXPRESSION