Human Umbilical Cord Mesenchymal Stem Cells: A New Era for Stem Cell Therapy

The human umbilical cord is a promising source of mesenchymal stem cells (HUCMSCs). Unlike bone marrow stem cells, HUCMSCs have a painless collection procedure and faster self-renewal properties. Different derivation protocols may provide different amounts and populations of stem cells. Stem cell po...

Full description

Saved in:

Bibliographic Details
Published in	Cell transplantation Vol. 24; no. 3; pp. 339 - 347
Main Authors	Ding, Dah-Ching, Chang, Yu-Hsun, Shyu, Woei-Cherng, Lin, Shinn-Zong
Format	Journal Article
Language	English
Published	Los Angeles, CA SAGE Publications 01.03.2015 SAGE Publishing
Subjects	Animals Biomarkers - metabolism Cell Differentiation Cell- and Tissue-Based Therapy Disease Models, Animal Humans Immunomodulation Mesenchymal Stem Cell Transplantation Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - metabolism Neoplasms - therapy Umbilical Cord - cytology Umbilical cord Wharton's jelly Clinical application Stem cells
Online Access	Get full text

Cover

Loading…

Abstract	The human umbilical cord is a promising source of mesenchymal stem cells (HUCMSCs). Unlike bone marrow stem cells, HUCMSCs have a painless collection procedure and faster self-renewal properties. Different derivation protocols may provide different amounts and populations of stem cells. Stem cell populations have also been reported in other compartments of the umbilical cord, such as the cord lining, perivascular tissue, and Wharton's jelly. HUCMSCs are noncontroversial sources compared to embryonic stem cells. They can differentiate into the three germ layers that promote tissue repair and modulate immune responses and anticancer properties. Thus, they are attractive autologous or allogenic agents for the treatment of malignant and nonmalignant solid and soft cancers. HUCMCs also can be the feeder layer for embryonic stem cells or other pluripotent stem cells. Regarding their therapeutic value, storage banking system and protocols should be established immediately. This review critically evaluates their therapeutic value, challenges, and future directions for their clinical applications.
AbstractList	The human umbilical cord is a promising source of mesenchymal stem cells (HUCMSCs). Unlike bone marrow stem cells, HUCMSCs have a painless collection procedure and faster self-renewal properties. Different derivation protocols may provide different amounts and populations of stem cells. Stem cell populations have also been reported in other compartments of the umbilical cord, such as the cord lining, perivascular tissue, and Wharton's jelly. HUCMSCs are noncontroversial sources compared to embryonic stem cells. They can differentiate into the three germ layers that promote tissue repair and modulate immune responses and anticancer properties. Thus, they are attractive autologous or allogenic agents for the treatment of malignant and nonmalignant solid and soft cancers. HUCMCs also can be the feeder layer for embryonic stem cells or other pluripotent stem cells. Regarding their therapeutic value, storage banking system and protocols should be established immediately. This review critically evaluates their therapeutic value, challenges, and future directions for their clinical applications. The human umbilical cord is a promising source of mesenchymal stem cells (HUCMSCs). Unlike bone marrow stem cells, HUCMSCs have a painless collection procedure and faster self-renewal properties. Different derivation protocols may provide different amounts and populations of stem cells. Stem cell populations have also been reported in other compartments of the umbilical cord, such as the cord lining, perivascular tissue, and Wharton's jelly. HUCMSCs are noncontroversial sources compared to embryonic stem cells. They can differentiate into the three germ layers that promote tissue repair and modulate immune responses and anticancer properties. Thus, they are attractive autologous or allogenic agents for the treatment of malignant and nonmalignant solid and soft cancers. HUCMCs also can be the feeder layer for embryonic stem cells or other pluripotent stem cells. Regarding their therapeutic value, storage banking system and protocols should be established immediately. This review critically evaluates their therapeutic value, challenges, and future directions for their clinical applications.The human umbilical cord is a promising source of mesenchymal stem cells (HUCMSCs). Unlike bone marrow stem cells, HUCMSCs have a painless collection procedure and faster self-renewal properties. Different derivation protocols may provide different amounts and populations of stem cells. Stem cell populations have also been reported in other compartments of the umbilical cord, such as the cord lining, perivascular tissue, and Wharton's jelly. HUCMSCs are noncontroversial sources compared to embryonic stem cells. They can differentiate into the three germ layers that promote tissue repair and modulate immune responses and anticancer properties. Thus, they are attractive autologous or allogenic agents for the treatment of malignant and nonmalignant solid and soft cancers. HUCMCs also can be the feeder layer for embryonic stem cells or other pluripotent stem cells. Regarding their therapeutic value, storage banking system and protocols should be established immediately. This review critically evaluates their therapeutic value, challenges, and future directions for their clinical applications.
Author	Chang, Yu-Hsun Lin, Shinn-Zong Shyu, Woei-Cherng Ding, Dah-Ching
Author_xml	– sequence: 1 givenname: Dah-Ching surname: Ding fullname: Ding, Dah-Ching – sequence: 2 givenname: Yu-Hsun surname: Chang fullname: Chang, Yu-Hsun – sequence: 3 givenname: Woei-Cherng surname: Shyu fullname: Shyu, Woei-Cherng – sequence: 4 givenname: Shinn-Zong surname: Lin fullname: Lin, Shinn-Zong
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/25622293$$D View this record in MEDLINE/PubMed
BookMark	eNp9kc1v1DAQxS1URLeFOyeUI5cUf8VOuFWrQistcKCVuFkTe9x6lcSLnQjtf4_bLUWqBL5Ymvd7bzQzJ-RoihMS8pbRM6G5_kA7JVTbseaHalUr2QuyYk3T1KLt-BFZ3ct10fUxOcl5SynVgjevyDFvFOe8EyuyuVxGmKqbsQ9DsDBU65hc9QUzTvZuP5bC9xnHao3DkD9W59VX_FVdJKh8TH-V6voOE-z2r8lLD0PGN4__Kbn5dHG9vqw33z5frc83tZWqm2vWAxeC9dZ3DMtrqLcg2p72rIVW9Z56yqkGZ5VzgklFW5Q9Uwid5RKsOCVXh1wXYWt2KYyQ9iZCMA-FmG4NpDnYAY20TgvnKOfeSylFh1b7xlvpSk_QsmS9P2TtUvy5YJ7NGLItQ8GEccmGKc0VFZzTgr57RJd-RPfU-M82C0APgE0x54T-CWHU3B_MPD9YsahnFhtmmEOc5gRh-J-xPhgz3KLZxiVNZeX_5n8DNjOkkA
CitedBy_id	crossref_primary_10_1186_s13287_017_0535_0 crossref_primary_10_1007_s00441_022_03673_2 crossref_primary_10_1038_s41419_020_03045_0 crossref_primary_10_5812_mejrh_91843 crossref_primary_10_1016_j_bbrep_2023_101583 crossref_primary_10_1515_raon_2017_0022 crossref_primary_10_1111_cpr_12814 crossref_primary_10_1016_j_cryobiol_2024_104856 crossref_primary_10_1186_s13287_023_03587_y crossref_primary_10_1007_s10517_018_4305_5 crossref_primary_10_3390_polym10090997 crossref_primary_10_1590_1678_7757_2022_0375 crossref_primary_10_3390_macromol3020018 crossref_primary_10_1007_s00590_020_02630_5 crossref_primary_10_1016_j_colsurfb_2022_112799 crossref_primary_10_1111_cpr_13586 crossref_primary_10_2174_011574888X261128231108043931 crossref_primary_10_1016_j_actbio_2019_05_012 crossref_primary_10_1109_ACCESS_2021_3056553 crossref_primary_10_3389_fmolb_2023_1273113 crossref_primary_10_1016_j_sxmr_2019_08_003 crossref_primary_10_1253_circj_CJ_22_0257 crossref_primary_10_15283_ijsc21078 crossref_primary_10_3389_fimmu_2022_1034821 crossref_primary_10_1007_s10565_022_09759_5 crossref_primary_10_1302_2046_3758_103_BJR_2020_0206_R2 crossref_primary_10_2147_IJN_S433611 crossref_primary_10_3390_ijms21165905 crossref_primary_10_1177_09636897221089629 crossref_primary_10_7759_cureus_30529 crossref_primary_10_1089_cbr_2020_3855 crossref_primary_10_1038_s41598_021_94006_w crossref_primary_10_1016_j_bj_2021_02_001 crossref_primary_10_1186_s13287_018_0992_0 crossref_primary_10_1186_s13578_020_00466_4 crossref_primary_10_1186_s13287_021_02620_2 crossref_primary_10_1097_MD_0000000000025068 crossref_primary_10_1371_journal_pone_0309429 crossref_primary_10_1016_j_biomaterials_2018_07_017 crossref_primary_10_1016_j_jstrokecerebrovasdis_2020_105298 crossref_primary_10_1007_s00210_024_03269_3 crossref_primary_10_1007_s10853_024_10068_x crossref_primary_10_1097_MD_0000000000041075 crossref_primary_10_1016_j_ijbiomac_2019_06_246 crossref_primary_10_1016_j_bioadv_2022_213121 crossref_primary_10_1186_s12951_020_00708_0 crossref_primary_10_1002_jbm_a_35868 crossref_primary_10_3389_fbioe_2019_00337 crossref_primary_10_5005_jogyp_11012_0036 crossref_primary_10_1002_adhm_202302128 crossref_primary_10_1002_sctm_21_0027 crossref_primary_10_3389_fcell_2025_1558310 crossref_primary_10_2147_SCCAA_S248519 crossref_primary_10_1186_s10020_021_00272_9 crossref_primary_10_3390_ijms242015494 crossref_primary_10_1007_s10815_023_02960_3 crossref_primary_10_3892_ijmm_2019_4447 crossref_primary_10_1016_j_biomaterials_2019_119573 crossref_primary_10_1016_j_diabres_2022_109861 crossref_primary_10_1016_j_bbrep_2023_101458 crossref_primary_10_1186_s13287_019_1138_8 crossref_primary_10_1007_s12015_021_10192_0 crossref_primary_10_1016_j_cryobiol_2022_08_002 crossref_primary_10_1007_s00774_020_01090_5 crossref_primary_10_1177_15347346221095954 crossref_primary_10_2174_011574888X277276231215110316 crossref_primary_10_3389_fcell_2025_1517369 crossref_primary_10_1186_s13287_020_02072_0 crossref_primary_10_1089_ten_tea_2023_0370 crossref_primary_10_3390_jpm12040648 crossref_primary_10_3390_cells13100845 crossref_primary_10_1039_D0BM01221A crossref_primary_10_1038_srep40463 crossref_primary_10_1177_02611929231207774 crossref_primary_10_3390_vetsci6040090 crossref_primary_10_1186_s40001_019_0366_9 crossref_primary_10_3390_app131910617 crossref_primary_10_3390_ijms24054351 crossref_primary_10_1016_j_jcyt_2024_07_003 crossref_primary_10_1016_j_jcyt_2018_02_369 crossref_primary_10_4049_jimmunol_2300752 crossref_primary_10_3389_fmed_2023_1211070 crossref_primary_10_3727_096368915X690288 crossref_primary_10_1155_2017_4206187 crossref_primary_10_1021_acs_molpharmaceut_3c01121 crossref_primary_10_3390_ijms23169274 crossref_primary_10_3390_jcm14030683 crossref_primary_10_3923_ajcb_2016_1_12 crossref_primary_10_1007_s10517_018_4300_x crossref_primary_10_1016_j_colsurfa_2024_135992 crossref_primary_10_1007_s10517_019_04388_1 crossref_primary_10_1016_j_isci_2022_105657 crossref_primary_10_1007_s13770_022_00452_6 crossref_primary_10_1016_j_bbrc_2023_01_065 crossref_primary_10_15406_jsrt_2022_07_00153 crossref_primary_10_1007_s10517_016_3213_9 crossref_primary_10_1016_j_mtbio_2022_100226 crossref_primary_10_1134_S1990519X24010061 crossref_primary_10_1007_s11239_022_02694_6 crossref_primary_10_1186_s12974_022_02445_7 crossref_primary_10_3390_v15102094 crossref_primary_10_1016_j_pdpdt_2021_102480 crossref_primary_10_1016_j_actbio_2016_11_042 crossref_primary_10_1177_09636897221085901 crossref_primary_10_1007_s00580_016_2300_7 crossref_primary_10_1002_jcp_29004 crossref_primary_10_1631_jzus_B2300182 crossref_primary_10_1016_j_jneumeth_2018_11_019 crossref_primary_10_1080_17446651_2025_2457474 crossref_primary_10_1186_s13018_024_04651_w crossref_primary_10_31083_j_fbl2902074 crossref_primary_10_3390_ijms21010271 crossref_primary_10_1111_and_14440 crossref_primary_10_1080_14712598_2023_2214313 crossref_primary_10_3390_ijms19071853 crossref_primary_10_1038_s41598_024_56950_1 crossref_primary_10_1007_s10616_017_0177_1 crossref_primary_10_1002_jcb_30471 crossref_primary_10_1177_1055665620962360 crossref_primary_10_1007_s11033_020_06079_x crossref_primary_10_1016_j_reth_2021_08_003 crossref_primary_10_1155_2019_7951696 crossref_primary_10_1007_s10561_024_10129_0 crossref_primary_10_1002_stem_3069 crossref_primary_10_1155_2019_4961865 crossref_primary_10_1016_j_bj_2020_04_011 crossref_primary_10_4236_jcdsa_2021_111006 crossref_primary_10_3389_fendo_2025_1536655 crossref_primary_10_3390_cells10061491 crossref_primary_10_1155_2021_8293699 crossref_primary_10_1016_j_tice_2024_102346 crossref_primary_10_1111_jocd_13063 crossref_primary_10_1177_09636897221083252 crossref_primary_10_1016_j_actbio_2020_06_029 crossref_primary_10_1055_s_0044_1790231 crossref_primary_10_3389_fvets_2024_1443110 crossref_primary_10_1038_s41443_020_00406_3 crossref_primary_10_3390_biomedicines10123112 crossref_primary_10_1038_s41598_017_10655_w crossref_primary_10_3389_fbioe_2022_895998 crossref_primary_10_1186_s13287_024_03851_9 crossref_primary_10_1002_jbm_b_35131 crossref_primary_10_1089_jir_2021_0146 crossref_primary_10_1016_j_bioactmat_2023_06_012 crossref_primary_10_3389_fimmu_2017_00638 crossref_primary_10_3892_etm_2021_9642 crossref_primary_10_2174_1574888X18666221214123844 crossref_primary_10_18632_oncotarget_7456 crossref_primary_10_1038_s41598_024_74385_6 crossref_primary_10_1016_j_bj_2020_04_001 crossref_primary_10_1038_s41598_024_64263_6 crossref_primary_10_1155_2021_6619527 crossref_primary_10_2478_acb_2021_0016 crossref_primary_10_3389_fimmu_2022_923286 crossref_primary_10_1186_s13287_023_03559_2 crossref_primary_10_1007_s13770_017_0078_6 crossref_primary_10_1134_S1990519X16010065 crossref_primary_10_1016_j_acthis_2025_152237 crossref_primary_10_1007_s12035_024_04651_1 crossref_primary_10_3390_ijms26010225 crossref_primary_10_1002_adhm_202403122 crossref_primary_10_1186_s13018_023_04021_y crossref_primary_10_1016_j_acthis_2024_152184 crossref_primary_10_1186_s13063_023_07305_0 crossref_primary_10_1016_j_scr_2016_04_010 crossref_primary_10_1155_2018_8329174 crossref_primary_10_1080_00207454_2022_2042690 crossref_primary_10_4252_wjsc_v15_i11_999 crossref_primary_10_1007_s10557_023_07472_x crossref_primary_10_1186_s13287_021_02419_1 crossref_primary_10_1186_s13287_025_04203_x crossref_primary_10_3390_ijms25137235 crossref_primary_10_1186_s12891_020_03340_z crossref_primary_10_1016_S1875_5364_23_60419_4 crossref_primary_10_4252_wjsc_v12_i8_787 crossref_primary_10_1007_s12015_017_9759_8 crossref_primary_10_1016_j_reth_2022_07_005 crossref_primary_10_1155_2020_7430968 crossref_primary_10_3724_abbs_2021026 crossref_primary_10_1016_j_aanat_2018_06_006 crossref_primary_10_1016_j_addr_2023_114823 crossref_primary_10_1080_14767058_2023_2279931 crossref_primary_10_3390_ijms19071926 crossref_primary_10_1007_s12015_021_10221_y crossref_primary_10_1186_s13287_023_03375_8 crossref_primary_10_1002_btm2_10354 crossref_primary_10_1134_S1990519X15060061 crossref_primary_10_1186_s13287_020_1583_4 crossref_primary_10_1007_s13770_022_00450_8 crossref_primary_10_1016_j_yexcr_2021_112941 crossref_primary_10_3390_app11073000 crossref_primary_10_3390_ijms232314681 crossref_primary_10_1080_21655979_2021_1928441 crossref_primary_10_3340_jkns_2019_0146 crossref_primary_10_1111_ahe_12537 crossref_primary_10_3389_fcell_2015_00063 crossref_primary_10_1016_j_npep_2021_102125 crossref_primary_10_12677_ACM_2022_122208 crossref_primary_10_1007_s10495_022_01749_6 crossref_primary_10_17116_stomat202410305157 crossref_primary_10_3390_cells11030412 crossref_primary_10_1186_s12967_021_03226_1 crossref_primary_10_1007_s12035_016_0017_x crossref_primary_10_1186_s13287_021_02529_w crossref_primary_10_3390_ijms232415942 crossref_primary_10_1021_acsbiomaterials_3c01944 crossref_primary_10_1016_j_jot_2022_09_008 crossref_primary_10_1097_MOU_0000000000000636 crossref_primary_10_1016_j_tice_2023_102153 crossref_primary_10_1166_jbt_2022_3051 crossref_primary_10_1038_s41419_018_0323_5 crossref_primary_10_1007_s44164_022_00013_0 crossref_primary_10_32604_biocell_2022_016892 crossref_primary_10_1039_D2BM01472F crossref_primary_10_1002_cbin_11991 crossref_primary_10_1007_s13770_022_00440_w crossref_primary_10_1007_s10616_022_00523_5 crossref_primary_10_1007_s11010_022_04544_8 crossref_primary_10_3390_bioengineering9070274 crossref_primary_10_3390_pharmaceutics14040793 crossref_primary_10_1155_2022_1526217 crossref_primary_10_1166_jbn_2021_3155 crossref_primary_10_3390_ijms22063142 crossref_primary_10_1167_tvst_11_5_12 crossref_primary_10_3389_fendo_2023_1205901 crossref_primary_10_1039_C8RA01584H crossref_primary_10_1186_s13018_024_05029_8 crossref_primary_10_1155_2017_1732094 crossref_primary_10_1177_0963689721993774 crossref_primary_10_1186_s11658_018_0080_6 crossref_primary_10_3390_pharmaceutics12090896 crossref_primary_10_1002_tox_23544 crossref_primary_10_1007_s12015_022_10493_y crossref_primary_10_1186_s13287_024_04094_4 crossref_primary_10_1177_0885328217733378 crossref_primary_10_1016_j_lfs_2020_118002 crossref_primary_10_3390_cancers15112901 crossref_primary_10_3389_fbioe_2021_698614 crossref_primary_10_1016_j_bioactmat_2023_02_002 crossref_primary_10_1016_j_jot_2020_02_009 crossref_primary_10_1155_2019_7670316 crossref_primary_10_17151_biosa_2019_18_2_5 crossref_primary_10_1002_chem_201700002 crossref_primary_10_1016_j_arr_2023_102113 crossref_primary_10_1186_s13287_019_1184_2 crossref_primary_10_2139_ssrn_4200782 crossref_primary_10_4252_wjsc_v12_i8_879 crossref_primary_10_3892_mmr_2017_7950 crossref_primary_10_1088_1478_3975_aa5a61 crossref_primary_10_1186_s11658_019_0167_8 crossref_primary_10_1016_j_yexcr_2022_113296 crossref_primary_10_1089_scd_2018_0222 crossref_primary_10_1590_pboci_2024_020 crossref_primary_10_3389_fimmu_2021_785717 crossref_primary_10_34104_ajpab_021_085097 crossref_primary_10_1080_13697137_2022_2052841 crossref_primary_10_1016_j_xfss_2022_07_004 crossref_primary_10_1016_j_bioactmat_2022_08_023 crossref_primary_10_1002_smll_201805361 crossref_primary_10_12677_ACM_2021_1110645 crossref_primary_10_1016_j_apmt_2020_100690 crossref_primary_10_3389_fncel_2021_768711 crossref_primary_10_3390_biomedicines10112773 crossref_primary_10_3389_fimmu_2023_1127704 crossref_primary_10_1016_j_biocel_2019_02_001 crossref_primary_10_1038_s41585_023_00787_2 crossref_primary_10_1186_s13287_023_03365_w crossref_primary_10_1038_s42003_024_07024_5 crossref_primary_10_1186_s13063_019_3935_x crossref_primary_10_31857_S0041377123050061 crossref_primary_10_3389_fped_2017_00194 crossref_primary_10_1155_2024_3494652 crossref_primary_10_1016_j_bbrep_2018_10_007 crossref_primary_10_1007_s11596_024_2941_8 crossref_primary_10_1038_s41368_021_00152_2 crossref_primary_10_4103_1673_5374_380911 crossref_primary_10_4103_tcmj_tcmj_145_22 crossref_primary_10_2174_1574888X17666220127110332 crossref_primary_10_4252_wjsc_v16_i12_990 crossref_primary_10_1016_j_cellsig_2023_110827 crossref_primary_10_1016_j_jcyt_2022_07_003 crossref_primary_10_1371_journal_pone_0184651 crossref_primary_10_1038_s41393_023_00884_4 crossref_primary_10_1038_s41598_017_02786_x crossref_primary_10_1186_s13287_025_04220_w crossref_primary_10_1016_j_ymthe_2020_02_003 crossref_primary_10_1007_s11033_022_07283_7 crossref_primary_10_1177_23259671221104409 crossref_primary_10_1371_journal_pone_0203936 crossref_primary_10_3389_fmed_2022_1073758 crossref_primary_10_2174_0109298673273833231220062213 crossref_primary_10_1016_j_ejps_2025_107053 crossref_primary_10_1155_2017_8749751 crossref_primary_10_4252_wjsc_v13_i12_1881 crossref_primary_10_34172_jlms_2020_73 crossref_primary_10_1093_jbcr_iraa207 crossref_primary_10_1177_09636897231156215 crossref_primary_10_1002_stem_2113 crossref_primary_10_4252_wjsc_v15_i6_502 crossref_primary_10_1155_2023_8014052 crossref_primary_10_1186_s12931_022_02192_6 crossref_primary_10_1016_j_apsb_2020_12_014 crossref_primary_10_1016_j_heliyon_2024_e37002 crossref_primary_10_48130_animadv_0024_0008 crossref_primary_10_12677_ACM_2022_123284 crossref_primary_10_1155_2024_6202123 crossref_primary_10_1002_ibra_12152 crossref_primary_10_1007_s10517_015_3116_1 crossref_primary_10_3724_abbs_2023072 crossref_primary_10_1002_adtp_202200076 crossref_primary_10_1186_s40659_023_00459_w crossref_primary_10_3390_ijms25042350 crossref_primary_10_1016_j_biopha_2020_110789 crossref_primary_10_1016_j_lfs_2023_121646 crossref_primary_10_1186_s13287_020_01700_z crossref_primary_10_1186_s40001_023_01244_x crossref_primary_10_3389_fcell_2022_883996 crossref_primary_10_3390_ijms24108899 crossref_primary_10_1002_sctm_16_0492 crossref_primary_10_1186_s13018_019_1346_z crossref_primary_10_3892_etm_2018_6505 crossref_primary_10_1007_s13577_023_00922_6 crossref_primary_10_1097_MD_0000000000040490 crossref_primary_10_1016_j_bbrc_2023_149321 crossref_primary_10_3390_ijms241914477 crossref_primary_10_1186_s13287_023_03334_3 crossref_primary_10_3892_mmr_2018_8445 crossref_primary_10_1186_s13287_022_03167_6 crossref_primary_10_4252_wjsc_v14_i9_684 crossref_primary_10_1186_s13287_022_02973_2 crossref_primary_10_2174_0113892010316780240807104149 crossref_primary_10_2144_fsoa_2020_0036 crossref_primary_10_1016_j_imu_2022_101072 crossref_primary_10_1021_acsbiomaterials_9b00008 crossref_primary_10_3390_biomedicines10123082 crossref_primary_10_4103_1673_5374_369121 crossref_primary_10_1007_s10856_022_06681_4 crossref_primary_10_1039_C9TB02188D crossref_primary_10_55544_jrasb_2_1_1 crossref_primary_10_1038_s41598_017_12692_x crossref_primary_10_1007_s13577_023_01009_y crossref_primary_10_1002_btm2_10535 crossref_primary_10_1021_acsabm_3c01058 crossref_primary_10_2174_1574888X16666211007092055 crossref_primary_10_1039_D0TB02033H crossref_primary_10_2174_011574888X267673231120061600 crossref_primary_10_1016_j_intimp_2025_114285 crossref_primary_10_1186_s13287_025_04145_4 crossref_primary_10_1186_s12943_022_01650_5 crossref_primary_10_1186_s40659_023_00475_w crossref_primary_10_1007_s00018_017_2665_z crossref_primary_10_3390_cells14020082 crossref_primary_10_3892_mmr_2018_8413 crossref_primary_10_1155_2021_2989054 crossref_primary_10_1016_j_ejphar_2024_176719 crossref_primary_10_3390_cancers16162892 crossref_primary_10_1089_ten_tea_2023_0204 crossref_primary_10_1186_s12938_023_01096_w crossref_primary_10_3389_fimmu_2017_00462 crossref_primary_10_1186_s13287_020_02028_4 crossref_primary_10_1111_jog_12984 crossref_primary_10_1155_sci_7674219 crossref_primary_10_1007_s00404_024_07381_w crossref_primary_10_1016_j_bioactmat_2024_01_014 crossref_primary_10_1002_adhm_202202490 crossref_primary_10_12677_ACM_2022_124355 crossref_primary_10_1155_2020_1321283 crossref_primary_10_1093_stmcls_sxad053 crossref_primary_10_4103_1673_5374_293130 crossref_primary_10_1016_j_bbrep_2023_101497 crossref_primary_10_3390_ijms25073715 crossref_primary_10_1016_j_scr_2019_101475 crossref_primary_10_1007_s13205_024_03966_z crossref_primary_10_1021_acsami_0c22671 crossref_primary_10_1186_s12964_023_01451_3 crossref_primary_10_3390_ijms252312911 crossref_primary_10_1007_s13577_023_01007_0 crossref_primary_10_1097_YCO_0000000000000478 crossref_primary_10_1038_emm_2017_219 crossref_primary_10_3390_biom13010118 crossref_primary_10_7555_JBR_36_20220166 crossref_primary_10_1016_j_reth_2024_12_005
Cites_doi	10.1007/s12015-010-9214-6 10.1007/s00418-008-0519-3 10.2174/1875043501104010028 10.4252/wjsc.v6.i2.195 10.1089/ten.teb.2013.0664 10.1111/trf.12743 10.1016/j.stem.2010.09.009 10.1186/1423-0127-19-47 10.1634/stemcells.2007-1028 10.1186/1471-2407-10-590 10.1097/TP.0b013e3181a2a4b3 10.1038/sj.cgt.7701077 10.1038/nri2395 10.1146/annurev-bioeng-070909-105309 10.1007/s12185-009-0377-3 10.3727/096368912X647199 10.1111/j.1365-3148.2011.01076.x 10.1038/nature05934 10.1016/j.fertnstert.2010.03.027 10.1002/jcb.23395 10.4041/kjod.2012.42.6.307 10.3727/096368910X522270 10.3727/096368910X507204 10.1089/scd.2011.0441 10.1634/stemcells.2006-0071 10.1126/science.1251152 10.1089/cell.2009.0106 10.1126/science.1088547 10.1016/j.rbmo.2010.04.010 10.1007/s10549-011-1774-x 10.1053/j.gastro.2007.12.024 10.1634/stemcells.2007-0351 10.1038/nature09328 10.3727/096368910X514260 10.1111/imj.12044 10.1002/lt.21715 10.1007/s11626-011-9480-x 10.3727/096368910X 10.1089/scd.2009.0192 10.1016/S1472-6483(10)60539-1 10.1007/BF02256131 10.3727/096368914X678346 10.1126/science.284.5411.143 10.2174/156652412800619950 10.1038/nm.3569 10.1111/j.1582-4934.2011.01459.x 10.1016/j.canlet.2010.04.007 10.1038/nature09805 10.1634/stemcells.2007-0554 10.1016/j.nbd.2007.06.010 10.1007/s12015-014-9514-3 10.1158/0008-5472.CAN-08-2750 10.1016/j.canlet.2009.02.011 10.1089/scd.2009.0485 10.1016/j.intimp.2012.03.024 10.1177/1535370214539225 10.1007/s12015-010-9168-8 10.3727/096368910X514198 10.1002/jcb.24073 10.3727/096368911X586756 10.1089/ten.tea.2013.0333 10.1634/stemcells.21-1-50 10.1097/01.PGO.0000452207.26653.05 10.1038/nm1181 10.1007/s12015-011-9245-7 10.1634/stemcells.2004-0013 10.1093/humrep/deh279 10.2174/092986706779026237 10.1016/j.bbrc.2009.04.094 10.1155/2013/916136 10.1080/14653240600855905 10.1159/000343740 10.2174/1875043501205010050
ContentType	Journal Article
Copyright	2015 Cognizant Comm. Corp.
Copyright_xml	– notice: 2015 Cognizant Comm. Corp.
DBID	AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 DOA
DOI	10.3727/096368915X686841
DatabaseName	CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic DOAJ Directory of Open Access Journals
DatabaseTitle	CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic
DatabaseTitleList	CrossRef MEDLINE - Academic MEDLINE
Database_xml	– sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Engineering Anatomy & Physiology Biology
EISSN	1555-3892
EndPage	347
ExternalDocumentID	oai_doaj_org_article_4cd73dd022ff44439ec7f5fc4dfcaa74 25622293 10_3727_096368915X686841 10.3727_096368915X686841
Genre	Research Support, Non-U.S. Gov't Journal Article Review
GroupedDBID	--- --K 0R~ 0VX 1B1 29B 4.4 53G 54M 5GY 7X7 8FI 8FJ AAEDT AAGGD AALRI AAPEO AAQGT AAQXH AAQXK AASGM AAXUO ABDWY ABJIS ABQKF ABQXT ABUWG ABVFX ABWVN ABYTW ACARO ACFMA ACGBL ACLHI ACROE ACRPL ACVFH ADBBV ADCNI ADEIA ADMUD ADNMO ADOGD ADTBJ ADUKL AENEX AEUPX AEWDL AFCOW AFDWT AFKRA AFKRG AFPUW AFRWT AFYCX AGQPQ AJEFB AJMMQ AJUZI ALIPV ALMA_UNASSIGNED_HOLDINGS AOIJS APTNG AUTPY AYAKG BAWUL BCNDV BDDNI BENPR BPHCQ BSEHC BVXVI CBRKF CCPQU CORYS CQQTX CS3 DC. DU5 EBS EJD EMOBN F5P FDB FEDTE FGOYB FYUFA GROUPED_DOAJ H13 HMCUK HVGLF HYE HZ~ IHE J8X K.F M41 NQ- OK1 P2P PHGZM PHGZT PIMPY PQQKQ Q1R R2- R9- ROL RPM RPZ SAUOL SCDPB SCNPE SFC UHS UKHRP AAYXX ACHEB CITATION 31X AATBZ ACGZU ACSIQ AEWHI CGR CUY CVF DIK DV7 ECM EIF GROUPED_SAGE_PREMIER_JOURNAL_COLLECTION M4V NPM SFK SFT SGV SPP 7X8
ID	FETCH-LOGICAL-c469t-1ba2331bcf91eeee50fca38b0b18a86bf0f0207adc6dd314608e4b16ea9c24ac3
IEDL.DBID	AFRWT
ISSN	0963-6897 1555-3892
IngestDate	Wed Aug 27 01:31:22 EDT 2025 Fri Jul 11 09:53:38 EDT 2025 Thu Jan 02 22:16:27 EST 2025 Tue Jul 01 05:27:34 EDT 2025 Thu Apr 24 23:00:00 EDT 2025 Tue Jun 17 22:52:25 EDT 2025
IsDoiOpenAccess	true
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Issue	3
Keywords	Umbilical cord Wharton's jelly Clinical application Stem cells
Language	English
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c469t-1ba2331bcf91eeee50fca38b0b18a86bf0f0207adc6dd314608e4b16ea9c24ac3
Notes	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23
OpenAccessLink	https://doaj.org/article/4cd73dd022ff44439ec7f5fc4dfcaa74
PMID	25622293
PQID	1672603220
PQPubID	23479
PageCount	9
ParticipantIDs	doaj_primary_oai_doaj_org_article_4cd73dd022ff44439ec7f5fc4dfcaa74 proquest_miscellaneous_1672603220 pubmed_primary_25622293 crossref_primary_10_3727_096368915X686841 crossref_citationtrail_10_3727_096368915X686841 sage_journals_10_3727_096368915X686841
ProviderPackageCode	CITATION AAYXX
PublicationCentury	2000
PublicationDate	20150300
PublicationDateYYYYMMDD	2015-03-01
PublicationDate_xml	– month: 3 year: 2015 text: 20150300
PublicationDecade	2010
PublicationPlace	Los Angeles, CA
PublicationPlace_xml	– name: Los Angeles, CA – name: United States
PublicationTitle	Cell transplantation
PublicationTitleAlternate	Cell Transplant
PublicationYear	2015
Publisher	SAGE Publications SAGE Publishing
Publisher_xml	– name: SAGE Publications – name: SAGE Publishing
References	Chatzistamatiou, Papassavas, Michalopoulos, Gamaloutsos, Mallis, Gontika, Panagouli, Koussoulakos, Stavropoulos-Giokas 2014; 54 Wang, Han, Ma, Zuo, Geng, Gong, Sun, Li, Wang, Zhang, He, Han 2012; 21 Hsieh, Fu, Chang, Tsuang, Wang 2010; 19 El Omar, Beroud, Stoltz, Menu, Velot, Decot 2014; 20 Gore, Li, Fung, Young, Agarwal, Antosiewicz-Bourget, Canto, Giorgetti, Israel, Kiskinis, Lee, Loh, Manos, Montserrat, Panopoulos, Ruiz, Wilbert, Yu, Kirkness, Izpisua Belmonte, Rossi, Thomson, Eggan, Daley, Goldstein, Zhang 2011; 471 Wang, Hung, Peng, Huang, Wei, Guo, Fu, Lai, Chen 2004; 22 Wang, Shyu, Shen, Hsu, Chi, Chen, Huang, Shyr, Tang, Chen 2011; 20 Gong, Han, Zhao, Wang, Wang, Zhong, Wang, Wang, Wang, Sun, Han 2012; 21 Lee, Jung, Lee, Jeong, Cho, Hwang, Kim 2012; 13 Kim, Kwon, Im, Kim, Hwang, Holliday, Donatelli, Son, Jun 2012; 42 Reza, Ng, Gimeno, Phan, Ang 2011; 7 Ding, Shyu, Lin 2011; 20 Tsai, Lee, Chang, Hwang 2004; 19 Reza, Ng, Phan, Tan, Beuerman, Ang 2011; 7 Pittenger, Mackay, Beck, Jaiswal, Douglas, Mosca, Moorman, Simonetti, Craig, Marshak 1999; 284 Lim, Phan 2014; 23 Selmani, Naji, Zidi, Favier, Gaiffe, Obert, Borg, Saas, Tiberghien, Rouas-Freiss, Carosella, Deschaseaux 2008; 26 Okita, Ichisaka, Yamanaka 2007; 448 Ding, Shyu, Lin, Li 2006; 13 Ganta, Chiyo, Ayuzawa, Rachakatla, Pyle, Andrews, Weiss, Tamura, Troyer 2009; 69 La Rocca, Corrao, Lo Iacono, Corsello, Farina, Anzalone 2012; 5 Sinha, Jang, Oh, Khong, Wu, Manohar, Miller, Regalado, Loffredo, Pancoast, Hirshman, Lebowitz, Shadrach, Cerletti, Kim, Serwold, Goodyear, Rosner, Lee, Wagers 2014; 344 La Rocca, Anzalone, Corrao, Magno, Loria, Lo Iacono, Di Stefano, Giannuzzi, Marasa, Cappello, Zummo, Farina 2009; 131 Villeda, Plambeck, Middeldorp, Castellano, Mosher, Luo, Smith, Bieri, Lin, Berdnik, Wabl, Udeochu, Wheatley, Zou, Simmons, Xie, Longo, Wyss-Coray 2014; 20 Rachakatla, Marini, Weiss, Tamura, Troyer 2007; 14 Martin, Badell 2014; 34 Hacein-Bey-Abina, Von Kalle, Schmidt, McCormack, Wulffraat, Leboulch, Lim, Osborne, Pawliuk, Morillon, Sorensen, Forster, Fraser, Cohen, de Saint Basile, Alexander, Wintergerst, Frebourg, Aurias, Stoppa-Lyonnet, Romana, Radford-Weiss, Gross, Valensi, Delabesse, Macintyre, Sigaux, Soulier, Leiva, Wissler, Prinz, Rabbitts, Le Deist, Fischer, Cavazzana-Calvo 2003; 302 Manochantr, U-pratya, Kheolamai, Rojphisan, Chayosumrit, Tantrawatpan, Supokawej, Issaragrisil 2013; 43 Gauthaman, Yee, Cheyyatraivendran, Biswas, Choolani, Bongso 2012; 113 English, French, Wood 2010; 7 Fong, Gauthaman, Cheyyatraivendran, Lin, Biswas, Bongso 2012; 113 Mitchell, Weiss, Mitchell, Martin, Davis, Morales, Helwig, Beerenstrauch, Abou-Easa, Hildreth, Troyer, Medicetty 2003; 21 Fan, Zhang, Zhou 2011; 7 Ding, Shyu, Chiang, Lin, Chang, Wang, Su, Li 2007; 27 Salehinejad, Alitheen, Ali, Omar, Mohit, Janzamin, Samani, Torshizi, Nematollahi-Mahani 2012; 48 Martin, Muotri, Gage, Varki 2005; 11 Liu, Ding, Wang, Su, Lin, Li, Shyu 2010; 19 Ding, Shyu, Lin, Liu, Chiou, Chu 2012; 21 Ma, Hao, Zhang, Zhang 2012; 133 Yu, Long, Yu, Du, Ma, Ma, Yang, Fan 2013; 197 Gonzalez, Griparic, Umana, Burgee, Vargas, Nasrallah, Silva, Patel 2010; 19 Lai, Cheng, Liu, Jiang, Liu, Huang, Guo 2010; 12 Tsagias, Koliakos, Karagiannis, Eleftheriadou, Koliakos 2011; 21 Ma, Feng, Cui, Law, Jiang, Yang, Xie, Huang 2005; 118 Campard, Lysy, Najimi, Sokal 2008; 134 Lin, Fong, Biswas, Choolani, Bongso 2014; 10 Cavazzana-Calvo, Payen, Negre, Wang, Hehir, Fusil, Down, Denaro, Brady, Westerman, Cavallesco, Gillet-Legrand, Caccavelli, Sgarra, Maouche-Chretien, Bernaudin, Girot, Dorazio, Mulder, Polack, Bank, Soulier, Larghero, Kabbara, Dalle, Gourmel, Socie, Chretien, Cartier, Aubourg, Fischer, Cornetta, Galacteros, Beuzard, Gluckman, Bushman, Hacein-Bey-Abina, Leboulch 2010; 467 Chang, Yen, Chen, Chien, Huang, Bai, Yen 2006; 24 Fong, Subramanian, Biswas, Gauthaman, Srikanth, Hande, Bongso 2010; 21 Selmani, Naji, Gaiffe, Obert, Tiberghien, Rouas-Freiss, Carosella, Deschaseaux 2009; 87 Saben, Thakali, Lindsey, Zhong, Badger, Andres, Shankar 2014; 239 He, Nagamura-Inoue, Tsunoda, Yuzawa, Yamamoto, Yorozu, Agata, Tojo 2014; 20 Maurya, Doi, Kawabata, Pyle, King, Wu, Troyer, Tamura 2010; 10 Fu, Shih, Cheng, Min 2004; 11 Chao, Yang, Chen 2012; 16 Cho, Lee, Nam, Yang, Cho, Lim, Lee 2010; 93 Seo, Lee, Bhandari, Roh, Park, So, Jung, Seo, Kang, Lee, Kang 2009; 384 Ding, Wu, Chou, Hung, Liu, Chu 2014 Mennan, Wright, Bhattacharjee, Balain, Richardson, Roberts 2013; 2013 Nagamura-Inoue, He 2014; 6 Yamanaka, Takahashi 2006; 51 Weiss, Anderson, Medicetty, Seshareddy, Weiss, VanderWerff, Troyer, McIntosh 2008; 26 Tsai, Wang, Shyr, Weng, Tai, Shyu, Chen 2012; 19 Ayuzawa, Doi, Rachakatla, Pyle, Maurya, Troyer, Tamura 2009; 280 Tsai, Fu, Chen, Ko, Chen, Shih, Hung, Fu 2009; 15 Uccelli, Moretta, Pistoia 2008; 8 Ishige, Nagamura-Inoue, Honda, Harnprasopwat, Kido, Sugimoto, Nakauchi, Tojo 2009; 90 De Miguel, Fuentes-Julian, Blazquez-Martinez, Pascual, Aller, Arias, Arnalich-Montiel 2012; 12 Dominici, Le Blanc, Mueller, Slaper-Cortenbach, Marini, Krause, Deans, Keating, Prockop, Horwitz 2006; 8 Kita, Gauglitz, Phan, Herndon, Jeschke 2010; 19 Greco, Liu, Rameshwar 2007; 25 Lin, Chang, Liu, Chang, Sun, Li, Luo, Liao, Chen, Chen, Lee, Yang, Harn, Chiou 2010; 19 Prasanna, Jahnavi 2011; 4 Sun, Yu, Bhandari, Jung, Kang, Kang 2010; 296 Fong, Richards, Manasi, Biswas, Bongso 2007; 15 Parekkadan, Milwid 2010; 12 bibr16-096368915X686841 bibr59-096368915X686841 bibr67-096368915X686841 bibr24-096368915X686841 bibr41-096368915X686841 bibr2-096368915X686841 bibr50-096368915X686841 bibr33-096368915X686841 bibr17-096368915X686841 bibr4-096368915X686841 bibr68-096368915X686841 bibr3-096368915X686841 bibr25-096368915X686841 bibr51-096368915X686841 bibr34-096368915X686841 bibr77-096368915X686841 bibr35-096368915X686841 bibr22-096368915X686841 bibr30-096368915X686841 bibr27-096368915X686841 bibr43-096368915X686841 bibr14-096368915X686841 bibr56-096368915X686841 bibr69-096368915X686841 bibr74-096368915X686841 bibr48-096368915X686841 bibr61-096368915X686841 Yamanaka S. (bibr76-096368915X686841) 2006; 51 bibr66-096368915X686841 bibr9-096368915X686841 bibr53-096368915X686841 bibr58-096368915X686841 bibr6-096368915X686841 bibr40-096368915X686841 Ding D. C. (bibr13-096368915X686841) 2014 bibr19-096368915X686841 bibr32-096368915X686841 bibr71-096368915X686841 bibr45-096368915X686841 bibr1-096368915X686841 bibr54-096368915X686841 bibr11-096368915X686841 bibr29-096368915X686841 bibr7-096368915X686841 bibr20-096368915X686841 bibr70-096368915X686841 bibr37-096368915X686841 bibr46-096368915X686841 bibr63-096368915X686841 Ma L. (bibr42-096368915X686841) 2005; 118 bibr47-096368915X686841 bibr72-096368915X686841 bibr12-096368915X686841 bibr55-096368915X686841 bibr8-096368915X686841 bibr64-096368915X686841 bibr38-096368915X686841 bibr21-096368915X686841 bibr60-096368915X686841 bibr73-096368915X686841 bibr5-096368915X686841 William P. L. (bibr75-096368915X686841) 1995 bibr57-096368915X686841 bibr26-096368915X686841 bibr18-096368915X686841 bibr44-096368915X686841 bibr52-096368915X686841 bibr39-096368915X686841 bibr31-096368915X686841 bibr65-096368915X686841 bibr10-096368915X686841 bibr23-096368915X686841 bibr15-096368915X686841 bibr28-096368915X686841 bibr36-096368915X686841 bibr49-096368915X686841 bibr62-096368915X686841
References_xml	– volume: 87 start-page: S62 issue: 9 year: 2009 end-page: 66 article-title: HLA-G is a crucial immunosuppressive molecule secreted by adult human mesenchymal stem cells. publication-title: Transplantation – volume: 280 start-page: 31 issue: 1 year: 2009 end-page: 37 article-title: Naive human umbilical cord matrix derived stem cells significantly attenuate growth of human breast cancer cells in vitro and in vivo. publication-title: Cancer Lett. – volume: 27 start-page: 339 issue: 3 year: 2007 end-page: 353 article-title: Enhancement of neuroplasticity through up-regulation of betal-integrin in human umbilical cord-derived stromal cell implanted stroke model. publication-title: Neurobiol. Dis. – volume: 2013 start-page: 916136 year: 2013 article-title: Isolation and characterisation of mesenchymal stem cells from different regions of the human umbilical cord. publication-title: Biomed. Res. Int. – volume: 54 start-page: 3108 issue: 12 year: 2014 end-page: 3120 article-title: Optimizing isolation culture and freezing methods to preserve Wharton's jelly's mesenchymal stem cell (MSC) properties: An MSC banking protocol validation for the Hellenic Cord Blood Bank. publication-title: Transfusion – volume: 22 start-page: 1330 issue: 7 year: 2004 end-page: 1337 article-title: Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord. publication-title: Stem Cells – volume: 21 start-page: 1401 issue: 9 year: 2012 end-page: 1408 article-title: A toxicity study of multiple-administration human umbilical cord mesenchymal stem cells in cynomolgus monkeys. publication-title: Stem Cells Dev. – volume: 133 start-page: 473 issue: 2 year: 2012 end-page: 485 article-title: The in vitro and in vivo effects of human umbilical cord mesenchymal stem cells on the growth of breast cancer cells. publication-title: Breast Cancer Res. Treat. – volume: 284 start-page: 143 issue: 5411 year: 1999 end-page: 147 article-title: Multilineage potential of adult human mesenchymal stem cells. publication-title: Science – volume: 197 start-page: 209 issue: 3 year: 2013 end-page: 223 article-title: Analysis of differentiation potentials and gene expression profiles of mesenchymal stem cells derived from periodontal ligament and Wharton's jelly of the umbilical cord. publication-title: Cells Tissues Organs – volume: 12 start-page: 87 year: 2010 end-page: 117 article-title: Mesenchymal stem cells as therapeutics. publication-title: Annu. Rev. Biomed. Eng. – volume: 19 start-page: 1261 issue: 10 year: 2010 end-page: 1279 article-title: Non-senescent Hsp27-upregulated MSCs implantation promotes neuroplasticity in stroke model. publication-title: Cell Transplant. – volume: 296 start-page: 178 issue: 2 year: 2010 end-page: 185 article-title: Human umbilical cord blood mesenchymal stem cell-derived extracellular matrix prohibits metastatic cancer cell MDA-MB-231 proliferation. publication-title: Cancer Lett. – volume: 19 start-page: 1450 issue: 6 year: 2004 end-page: 1456 article-title: Isolation of human multi-potent mesenchymal stem cells from second-trimester amniotic fluid using a novel two-stage culture protocol. publication-title: Hum. Reprod. – volume: 471 start-page: 63 issue: 7336 year: 2011 end-page: 67 article-title: Somatic coding mutations in human induced pluripotent stem cells. publication-title: Nature – volume: 8 start-page: 315 issue: 4 year: 2006 end-page: 317 article-title: Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. publication-title: Cytotherapy – volume: 6 start-page: 195 issue: 2 year: 2014 end-page: 202 article-title: Umbilical cord-derived mesenchymal stem cells: Their advantages and potential clinical utility. publication-title: World J. Stem Cells – volume: 7 start-page: 935 issue: 4 year: 2011 end-page: 947 article-title: Umbilical cord lining stem cells as a novel and promising source for ocular surface regeneration. publication-title: Stem Cell Rev. – volume: 10 start-page: 590 year: 2010 article-title: Therapy with un-engineered naive rat umbilical cord matrix stem cells markedly inhibits growth of murine lung adenocarcinoma. publication-title: BMC Cancer – volume: 302 start-page: 415 issue: 5644 year: 2003 end-page: 419 article-title: LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. publication-title: Science – volume: 20 start-page: 5 issue: 1 year: 2011 end-page: 14 article-title: Mesenchymal stem cells. publication-title: Cell Transplant. – volume: 7 start-page: 431 issue: 4 year: 2010 end-page: 442 article-title: Mesenchymal stromal cells: Facilitators of successful transplantation? publication-title: Cell Stem Cell – volume: 42 start-page: 307 issue: 6 year: 2012 end-page: 317 article-title: Differentiation and characteristics of undifferentiated mesenchymal stem cells originating from adult premolar periodontal ligaments. publication-title: Korean J. Orthod. – volume: 51 start-page: 2346 issue: 15 year: 2006 end-page: 2351 article-title: [Induction of pluripotent stem cells from mouse fibroblast cultures]. publication-title: Tanpakushitsu Kakusan Koso – volume: 21 start-page: 50 issue: 1 year: 2003 end-page: 60 article-title: Matrix cells from Wharton's jelly form neurons and glia. publication-title: Stem Cells – volume: 13 start-page: 219 issue: 2 year: 2012 end-page: 224 article-title: Comparison of immuno-modulatory effects of placenta mesenchymal stem cells with bone marrow and adipose mesenchymal stem cells. publication-title: Int. Immunopharmacol. – volume: 12 start-page: 305 issue: 3 year: 2010 end-page: 314 article-title: Optimization of culture conditions to support undifferentiated growth of human embryonic stem cells. publication-title: Cell. Reprogram. – volume: 12 start-page: 574 issue: 5 year: 2012 end-page: 591 article-title: Immuno-suppressive properties of mesenchymal stem cells: Advances and applications. publication-title: Curr. Mol. Med. – volume: 11 start-page: 652 issue: 5 year: 2004 end-page: 660 article-title: Transformation of human umbilical mesenchymal cells into neurons in vitro. publication-title: J. Biomed. Sci. – volume: 131 start-page: 267 issue: 2 year: 2009 end-page: 282 article-title: Isolation and characterization of Oct-4+/HLA-G+ mesenchymal stem cells from human umbilical cord matrix: Differentiation potential and detection of new markers. publication-title: Histochem. Cell Biol. – volume: 26 start-page: 2865 issue: 11 year: 2008 end-page: 2874 article-title: Immune properties of human umbilical cord Wharton's jelly-derived cells. publication-title: Stem Cells – year: 2014 article-title: Human infra-patellar fat pad-derived stromal cells have more potent differentiation capacity than other mesenchymal cells and can be enhanced by hyaluronan. publication-title: Cell Transplant. – volume: 467 start-page: 318 issue: 7313 year: 2010 end-page: 322 article-title: Transfusion independence and HMGA2 activation after gene therapy of human beta-thalassaemia. publication-title: Nature – volume: 448 start-page: 313 issue: 7151 year: 2007 end-page: 317 article-title: Generation of germline-competent induced pluripotent stem cells. publication-title: Nature – volume: 69 start-page: 1815 issue: 5 year: 2009 end-page: 1820 article-title: Rat umbilical cord stem cells completely abolish rat mammary carcinomas with no evidence of metastasis or recurrence 100 days post-tumor cell inoculation. publication-title: Cancer Res. – volume: 21 start-page: 207 issue: 1 year: 2012 end-page: 216 article-title: Banking human umbilical cord-derived mesenchymal stromal cells for clinical use. publication-title: Cell Transplant. – volume: 34 start-page: 1 issue: 15 year: 2014 end-page: 6 article-title: Umbilical cord blood banking. publication-title: Postgrad. Obstet. Gynecol. – volume: 26 start-page: 212 issue: 1 year: 2008 end-page: 222 article-title: Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cells. publication-title: Stem Cells – volume: 90 start-page: 261 issue: 2 year: 2009 end-page: 269 article-title: Comparison of mesenchymal stem cells derived from arterial, venous, and Wharton's jelly explants of human umbilical cord. publication-title: Int. J. Hematol. – volume: 23 start-page: 497 issue: 4-5 year: 2014 end-page: 503 article-title: Epithelial and mesenchymal stem cells from the umbilical cord lining membrane. publication-title: Cell Transplant. – volume: 239 start-page: 1340 issue: 10 year: 2014 end-page: 1351 article-title: Distinct adipogenic differentiation phenotypes of human umbilical cord mesenchymal cells dependent on adipogenic conditions. publication-title: Exp. Biol. Med. – volume: 384 start-page: 120 issue: 1 year: 2009 end-page: 125 article-title: OCT4A contributes to the stemness and multi-potency of human umbilical cord blood-derived multipotent stem cells (hUCB-MSCs). publication-title: Biochem. Biophys. Res. Commun. – volume: 15 start-page: 484 issue: 5 year: 2009 end-page: 495 article-title: The therapeutic potential of human umbilical mesenchymal stem cells from Wharton's jelly in the treatment of rat liver fibrosis. publication-title: Liver Transpl. – volume: 344 start-page: 649 issue: 6184 year: 2014 end-page: 652 article-title: Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle. publication-title: Science – volume: 48 start-page: 75 issue: 2 year: 2012 end-page: 83 article-title: Comparison of different methods for the isolation of mesenchymal stem cells from human umbilical cord Wharton's jelly. In Vitro Cell Dev. publication-title: Biol. Anim. – volume: 13 start-page: 3565 issue: 29 year: 2006 end-page: 3574 article-title: Current concepts in adult stem cell therapy for stroke. publication-title: Curr. Med. Chem. – volume: 7 start-page: 624 issue: 3 year: 2011 end-page: 638 article-title: Characterization of a novel umbilical cord lining cell with CD227 positivity and unique pattern of P63 expression and function. publication-title: Stem Cell Rev. – volume: 113 start-page: 658 issue: 2 year: 2012 end-page: 668 article-title: Human umbilical cord Wharton's jelly stem cells and its conditioned medium support hematopoietic stem cell expansion ex vivo. publication-title: J. Cell. Biochem. – volume: 19 start-page: 491 issue: 4 year: 2010 end-page: 502 article-title: Isolation and characterization of mesenchymal stem cells from the sub-amniotic human umbilical cord lining membrane. publication-title: Stem Cells Dev. – volume: 43 start-page: 430 issue: 4 year: 2013 end-page: 439 article-title: Immunosuppressive properties of mesenchymal stromal cells derived from amnion, placenta, Wharton's jelly and umbilical cord. publication-title: Intern. Med. J. – volume: 118 start-page: 1987 issue: 23 year: 2005 end-page: 1993 article-title: Human umbilical cord Wharton's Jelly-derived mesenchymal stem cells differentiation into nerve-like cells. publication-title: Chin. Med. J. – volume: 20 start-page: 455 issue: 3 year: 2011 end-page: 466 article-title: Transplantation of insulin-producing cells derived from umbilical cord stromal mesenchymal stem cells to treat NOD mice. publication-title: Cell Transplant. – volume: 20 start-page: 1314 issue: 7-8 year: 2014 end-page: 1324 article-title: Stage-specific embryonic antigen 4 in Wharton's jelly-derived mesenchymal stem cells is not a marker for proliferation and multipotency. publication-title: Tissue Eng. Part A – volume: 19 start-page: 1451 issue: 11 year: 2010 end-page: 1463 article-title: Transplantation of human Wharton's Jelly-derived stem cells alleviates chemically induced liver fibrosis in rats. publication-title: Cell Transplant. – volume: 5 start-page: 50 year: 2012 end-page: 58 article-title: Novel immuno-modulatory markers expressed by human WJ-MSC: An update review in regenerative and reparative medicine. publication-title: Open Tissue Eng. Reg. Med. J. – volume: 10 start-page: 573 issue: 4 year: 2014 end-page: 586 article-title: Human Wharton's jelly stem cells, its conditioned medium and cell-free lysate inhibit the growth of human lymphoma cells. publication-title: Stem Cell Rev. – volume: 25 start-page: 3143 issue: 12 year: 2007 end-page: 3154 article-title: Functional similarities among genes regulated by OCT4 in human mesenchymal and embryonic stem cells. publication-title: Stem Cells – volume: 20 start-page: 659 issue: 6 year: 2014 end-page: 663 article-title: Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. publication-title: Nat. Med. – volume: 19 start-page: 1439 issue: 11 year: 2010 end-page: 1449 article-title: An efficient approach to isolation and characterization of pre- and post-natal umbilical cord lining stem cells for clinical applications. publication-title: Cell Transplant. – volume: 14 start-page: 828 issue: 10 year: 2007 end-page: 835 article-title: Development of human umbilical cord matrix stem cell-based gene therapy for experimental lung tumors. publication-title: Cancer Gene Ther. – volume: 21 start-page: 253 issue: 4 year: 2011 end-page: 261 article-title: Isolation of mesenchymal stem cells using the total length of umbilical cord for transplantation purposes. publication-title: Transfus. Med. – volume: 16 start-page: 1803 issue: 8 year: 2012 end-page: 1815 article-title: Human umbilical cord mesenchymal stem cells suppress breast cancer tumourigenesis through direct cell-cell contact and internalization. publication-title: J. Cell. Mol. Med. – volume: 24 start-page: 2466 issue: 11 year: 2006 end-page: 2477 article-title: Placenta-derived multipotent cells exhibit immunosuppressive properties that are enhanced in the presence of interferon-gamma. publication-title: Stem Cells – volume: 134 start-page: 833 issue: 3 year: 2008 end-page: 848 article-title: Native umbilical cord matrix stem cells express hepatic markers and differentiate into hepatocyte-like cells. publication-title: Gastroenterology – volume: 21 start-page: 1515 issue: 7 year: 2012 end-page: 1527 article-title: Human umbilical cord mesenchymal stem cells support non-tumorigenic expansion of human embryonic stem cells. publication-title: Cell Transplant. – volume: 11 start-page: 228 issue: 2 year: 2005 end-page: 232 article-title: Human embryonic stem cells express an immunogenic nonhuman sialic acid. publication-title: Nat. Med. – volume: 4 start-page: 28 year: 2011 end-page: 38 article-title: Wharton's jelly mesenchymal stem cells as off-the-shelf cellular therapeutics: A closer look into their regenerative and immuno-modulatory properties. publication-title: Open Tissue Eng. Reg. Med. J. – volume: 19 start-page: 1895 issue: 12 year: 2010 end-page: 1910 article-title: Functional module analysis reveals differential osteogenic and stemness potentials in human mesenchymal stem cells from bone marrow and Wharton's jelly of umbilical cord. publication-title: Stem Cells Dev. – volume: 20 start-page: 523 issue: 5 year: 2014 end-page: 544 article-title: Umbilical cord mesenchymal stem cells: The new gold standard for mesenchymal stem cell-based therapies? publication-title: Tissue Eng. Part B Rev. – volume: 113 start-page: 2027 issue: 6 year: 2012 end-page: 2039 article-title: Human umbilical cord Wharton's jelly stem cell (hWJSC) extracts inhibit cancer cell growth in vitro. publication-title: J. Cell. Biochem. – volume: 19 start-page: 47 year: 2012 article-title: Transplantation of insulin-producing cells from umbilical cord mesenchymal stem cells for the treatment of streptozotocin-induced diabetic rats. publication-title: J. Biomed. Sci. – volume: 15 start-page: 708 issue: 6 year: 2007 end-page: 718 article-title: Comparative growth behaviour and characterization of stem cells from human Wharton's jelly. publication-title: Reprod. Biomed. Online – volume: 8 start-page: 726 issue: 9 year: 2008 end-page: 736 article-title: Mesenchymal stem cells in health and disease. publication-title: Nat. Rev. Immunol. – volume: 7 start-page: 195 issue: 1 year: 2011 end-page: 207 article-title: Therapeutic potentials of mesenchymal stem cells derived from human umbilical cord. publication-title: Stem Cell Rev. – volume: 93 start-page: 2525 issue: 8 year: 2010 end-page: 2531 article-title: Human feeder layer system derived from umbilical cord stromal cells for human embryonic stem cells. publication-title: Fertil. Steril. – volume: 21 start-page: 391 issue: 3 year: 2010 end-page: 401 article-title: Derivation efficiency, cell proliferation, freeze-thaw survival, stem-cell properties and differentiation of human Wharton's jelly stem cells. publication-title: Reprod. Biomed. Online – ident: bibr57-096368915X686841 doi: 10.1007/s12015-010-9214-6 – ident: bibr34-096368915X686841 doi: 10.1007/s00418-008-0519-3 – ident: bibr54-096368915X686841 doi: 10.2174/1875043501104010028 – ident: bibr50-096368915X686841 doi: 10.4252/wjsc.v6.i2.195 – ident: bibr15-096368915X686841 doi: 10.1089/ten.teb.2013.0664 – ident: bibr6-096368915X686841 doi: 10.1111/trf.12743 – ident: bibr16-096368915X686841 doi: 10.1016/j.stem.2010.09.009 – ident: bibr68-096368915X686841 doi: 10.1186/1423-0127-19-47 – ident: bibr74-096368915X686841 doi: 10.1634/stemcells.2007-1028 – year: 2014 ident: bibr13-096368915X686841 publication-title: Cell Transplant. – ident: bibr47-096368915X686841 doi: 10.1186/1471-2407-10-590 – ident: bibr60-096368915X686841 doi: 10.1097/TP.0b013e3181a2a4b3 – ident: bibr55-096368915X686841 doi: 10.1038/sj.cgt.7701077 – ident: bibr69-096368915X686841 doi: 10.1038/nri2395 – ident: bibr52-096368915X686841 doi: 10.1146/annurev-bioeng-070909-105309 – ident: bibr31-096368915X686841 doi: 10.1007/s12185-009-0377-3 – ident: bibr12-096368915X686841 doi: 10.3727/096368912X647199 – ident: bibr65-096368915X686841 doi: 10.1111/j.1365-3148.2011.01076.x – ident: bibr51-096368915X686841 doi: 10.1038/nature05934 – ident: bibr7-096368915X686841 doi: 10.1016/j.fertnstert.2010.03.027 – ident: bibr18-096368915X686841 doi: 10.1002/jcb.23395 – ident: bibr32-096368915X686841 doi: 10.4041/kjod.2012.42.6.307 – ident: bibr72-096368915X686841 doi: 10.3727/096368910X522270 – ident: bibr41-096368915X686841 doi: 10.3727/096368910X507204 – ident: bibr73-096368915X686841 doi: 10.1089/scd.2011.0441 – ident: bibr4-096368915X686841 doi: 10.1634/stemcells.2006-0071 – ident: bibr63-096368915X686841 doi: 10.1126/science.1251152 – ident: bibr36-096368915X686841 doi: 10.1089/cell.2009.0106 – ident: bibr28-096368915X686841 doi: 10.1126/science.1088547 – ident: bibr20-096368915X686841 doi: 10.1016/j.rbmo.2010.04.010 – ident: bibr43-096368915X686841 doi: 10.1007/s10549-011-1774-x – volume: 51 start-page: 2346 issue: 15 year: 2006 ident: bibr76-096368915X686841 publication-title: Tanpakushitsu Kakusan Koso – ident: bibr2-096368915X686841 doi: 10.1053/j.gastro.2007.12.024 – volume-title: Gray's anatomy. year: 1995 ident: bibr75-096368915X686841 – ident: bibr27-096368915X686841 doi: 10.1634/stemcells.2007-0351 – ident: bibr3-096368915X686841 doi: 10.1038/nature09328 – ident: bibr25-096368915X686841 doi: 10.3727/096368910X514260 – ident: bibr44-096368915X686841 doi: 10.1111/imj.12044 – ident: bibr67-096368915X686841 doi: 10.1002/lt.21715 – ident: bibr59-096368915X686841 doi: 10.1007/s11626-011-9480-x – ident: bibr10-096368915X686841 doi: 10.3727/096368910X – ident: bibr33-096368915X686841 doi: 10.1089/scd.2009.0192 – ident: bibr19-096368915X686841 doi: 10.1016/S1472-6483(10)60539-1 – ident: bibr21-096368915X686841 doi: 10.1007/BF02256131 – ident: bibr38-096368915X686841 doi: 10.3727/096368914X678346 – ident: bibr53-096368915X686841 doi: 10.1126/science.284.5411.143 – ident: bibr8-096368915X686841 doi: 10.2174/156652412800619950 – ident: bibr70-096368915X686841 doi: 10.1038/nm.3569 – ident: bibr5-096368915X686841 doi: 10.1111/j.1582-4934.2011.01459.x – ident: bibr64-096368915X686841 doi: 10.1016/j.canlet.2010.04.007 – ident: bibr26-096368915X686841 doi: 10.1038/nature09805 – ident: bibr61-096368915X686841 doi: 10.1634/stemcells.2007-0554 – ident: bibr9-096368915X686841 doi: 10.1016/j.nbd.2007.06.010 – ident: bibr39-096368915X686841 doi: 10.1007/s12015-014-9514-3 – ident: bibr22-096368915X686841 doi: 10.1158/0008-5472.CAN-08-2750 – ident: bibr1-096368915X686841 doi: 10.1016/j.canlet.2009.02.011 – ident: bibr30-096368915X686841 doi: 10.1089/scd.2009.0485 – ident: bibr37-096368915X686841 doi: 10.1016/j.intimp.2012.03.024 – ident: bibr58-096368915X686841 doi: 10.1177/1535370214539225 – volume: 118 start-page: 1987 issue: 23 year: 2005 ident: bibr42-096368915X686841 publication-title: Chin. Med. J. – ident: bibr17-096368915X686841 doi: 10.1007/s12015-010-9168-8 – ident: bibr40-096368915X686841 doi: 10.3727/096368910X514198 – ident: bibr23-096368915X686841 doi: 10.1002/jcb.24073 – ident: bibr24-096368915X686841 doi: 10.3727/096368911X586756 – ident: bibr29-096368915X686841 doi: 10.1089/ten.tea.2013.0333 – ident: bibr49-096368915X686841 doi: 10.1634/stemcells.21-1-50 – ident: bibr45-096368915X686841 doi: 10.1097/01.PGO.0000452207.26653.05 – ident: bibr46-096368915X686841 doi: 10.1038/nm1181 – ident: bibr56-096368915X686841 doi: 10.1007/s12015-011-9245-7 – ident: bibr71-096368915X686841 doi: 10.1634/stemcells.2004-0013 – ident: bibr66-096368915X686841 doi: 10.1093/humrep/deh279 – ident: bibr11-096368915X686841 doi: 10.2174/092986706779026237 – ident: bibr62-096368915X686841 doi: 10.1016/j.bbrc.2009.04.094 – ident: bibr48-096368915X686841 doi: 10.1155/2013/916136 – ident: bibr14-096368915X686841 doi: 10.1080/14653240600855905 – ident: bibr77-096368915X686841 doi: 10.1159/000343740 – ident: bibr35-096368915X686841 doi: 10.2174/1875043501205010050
SSID	ssj0007325
Score	2.596086
SecondaryResourceType	review_article
Snippet	The human umbilical cord is a promising source of mesenchymal stem cells (HUCMSCs). Unlike bone marrow stem cells, HUCMSCs have a painless collection procedure...
SourceID	doaj proquest pubmed crossref sage
SourceType	Open Website Aggregation Database Index Database Enrichment Source Publisher
StartPage	339
SubjectTerms	Animals Biomarkers - metabolism Cell Differentiation Cell- and Tissue-Based Therapy Disease Models, Animal Humans Immunomodulation Mesenchymal Stem Cell Transplantation Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - metabolism Neoplasms - therapy Umbilical Cord - cytology
SummonAdditionalLinks	– databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1LSwMxEA5SEPQgvl1fRBDBw9JN89p6a4siol600NuSJx7arbT14L93kt3WBz4u7mnJZnfDzGTmm2Qyg9CptVyDmePgm2RZyhhtpdpbmgJYNtoyKhkLp5Hv7sV1n90M-OBDqa8QE1alB64I12TGSmotmBrvGXyr7Yz03BtmvVFKxkygYPPmzlStgyWN5VYBn9NU5G1ZbVBSMNbN0AZNhA9ELnJGPhmkmLf_O7D5KdAr2p6rdbRWg0bcqQa7gZZcuYm2OiU4zKNXfIZjGGdcH99Ey9353eqHXINb6DYu1-P-KETDAmNwD9xOfBcOH5mn1xE0PMzcCPfccDi9wB0M2g9fThQGUPv-BD9WSQi2Uf_q8rF3ndalFFID_u8sJVq1KCXa-DZxcPEMqEdznWmSq1xon3nAjVJZI6yloD2z3DFNhFNt02LK0B3UKMel2wuHvKkVXgpLFGfaENXihnlBQVMYoKhMUHNOz8LUecZDuYthAf5G4EDxlQMJOl-88Vzl2PilbzewaNEvZMeODSAzRS0zxV8yk6CTOYMLmE1hi0SVbvwyLYiQ4OCBkssStFtxfvErAIeh-DlN0FkQhaKe7NMfx7r_H2M9QCuA0XgV9naIGrPJizsCHDTTx1Hk3wBCt_10 priority: 102 providerName: Directory of Open Access Journals
Title	Human Umbilical Cord Mesenchymal Stem Cells: A New Era for Stem Cell Therapy
URI	https://journals.sagepub.com/doi/full/10.3727/096368915X686841 https://www.ncbi.nlm.nih.gov/pubmed/25622293 https://www.proquest.com/docview/1672603220 https://doaj.org/article/4cd73dd022ff44439ec7f5fc4dfcaa74
Volume	24
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
link	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1JbxMxFLZKKyQ4IGhZhqUyEqrEYeh4vE24oDRqVCHKARKR28hrOWQmVZZD_n3fmyVQVBA5RY4TT_wWf-_5LYS8815aOOYk2CZZlgrB89RGz1MAy856wbUQmI18-VVdTMXnmZztkbrPhel2cPUBw6rgiRpljdKN3mgUcQ4H7ingbq6KAZMzVahCsE-bdVW23u6-qQaO4PX0psKbbYfxkNu0z267Rw5yrSQI8sFw_O3HZKe7NW_atOLvp7CAbi8271zz1kHW1Pu_C6TeChBrzqzxY_KoA5t02HLHE7IX6kNyNKzB0K629IQ24Z-NX_2Q3D_r3z38rUbhEfnSuPnptMIoWiAoHYG5Si8xacn93FYw8H0dKjoK8_nqIx1S0Jr0fGkogOFfn9BJW7zgKZmOzyeji7RrwZA6sJvXKbMm55xZFwcswEtm0Rle2MyywhTKxiwC3tTGO-U9B62bFUFYpoIZuFwYx5-R_XpRhxeYHM69ilp5ZqSwjplcOhEVBw3jYEd1Qk77_SxdV58c22TMS7BTkALlnxRIyPvdN67b2hz_mHuGJNrNw6razcBieVV2QloK5zX3HmBNjAL4dhCcjjI64eFfGy0S8rYncAlSiFcrpg6LzapkSoNhCMoxS8jzlvK7pQBUYtN0npATZIWyZ_G_PuvL_534ijwA_CbbkLjXZH-93IQ3gJHW9rhj7OPGx3ADatQIAw
linkProvider	SAGE Publications
linkToHtml	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1Lj9MwEB6hrhBwQLDLIzyNhFbiEDauXym3brVVgXYP0IreLD_h0Kao7R723zNO0rKLFkROkTNOHI898409ngF4672wqOYE2iZFkXPOurmNnuUIlp31nCnO02nkybkczfinuZhfSfXV9uDmfXKrwhbVwrqd3Qx17QlCbibLHhVzWcoyHVk_4ElpdeCgP_zybboXw4rVGVcTfY4VVLNHeeM7rumkOnT_TXjzmq9XrX6GD-B-ixtJv2H0Q7gVqkM46ldoMy8vyTGpPTnrJfJDuH26u7t3JdzgEYzrFXsyWyaHWOQNGaDlSSbp_JH7cbnEgq_bsCSDsFhsPpA-QQFIztaGIK79_YRMmzgEj2A2PJsORnmbTSF3aAJvc2pNlzFqXezRgJcoojOstIWlpSmljUVE6KiMd9J7hgK0KAO3VAbTc11uHHsMnWpVhafpnDfzMirpqRHcOmq6wvEoGQoLhz2qMjjZ9ad2bajxlPFiodHkSBzQf3Igg3f7Gj-bMBv_oD1NLNrTpQDZdcFq_V23801z5xXzHhFKjByHYC84FUV03ONfG8UzeLNjsMYJlXZJTBVWFxtNpUIbD-VckcGThvP7TyE-TPnPWQbHaSjo3Wj9a1uf_S_ha7gzmk7Gevzx_PNzuIuwTDSebi-gs11fhJcIfbb2VTvIfwGO5fRo
linkToPdf	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3db9MwED-hTiB4QGPjI7CBkdAkHsLi-ivlrSurBmwTglb0zfInPLTp1HYP--85J2nH0EDkKXLOieOz735n350B3ngvLKo5gbZJUeScs25uo2c5gmVnPWeK8xSNfHYuT8b800RMWt-cFAvT9uDyXXKrwhbVwjrN7gsf0wxnqG8PEXYzWfaomMhSlilsfYtzVI0d2OoPv34fbUSxYvWpq4k-xwqq2ae89R039FKdvv82zHnD36tWQcNteNhiR9JvmP0I7oRqB3b7FdrNsytyQGpvznqZfAfuHq3vHvyWcnAXTutVezKeJadY5A8ZoPVJzlIMkvt5NcOCb6swI4MwnS7fkz5BIUiOF4Ygtr1-QkZNLoLHMB4ejwYneXuiQu7QDF7l1JouY9S62KMBL1FEZ1hpC0tLU0obi4jwURnvpPcMhWhRBm6pDKbnutw49gQ61bwKz1KsN_MyKumpEdw6arrC8SgZCgyHPaoyOFz3p3ZtuvF06sVUo9mROKD_5EAGbzc1LppUG_-gPUos2tClJNl1wXzxQ7dzTnPnFfMeUUqMHIdhLzgVRXTc418bxTN4vWawxkmVdkpMFeaXS02lQjsPZV2RwdOG85tPIUZMZ6CzDA7SUNDrEfvXtj7_X8JXcO_Lh6E-_Xj--QXcR2QmGme3PeisFpdhH9HPyr5sx_gvUVX1eA
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Human+umbilical+cord+mesenchymal+stem+cells%3A+a+new+era+for+stem+cell+therapy&rft.jtitle=Cell+transplantation&rft.au=Ding%2C+Dah-Ching&rft.au=Chang%2C+Yu-Hsun&rft.au=Shyu%2C+Woei-Cherng&rft.au=Lin%2C+Shinn-Zong&rft.date=2015-03-01&rft.eissn=1555-3892&rft.volume=24&rft.issue=3&rft.spage=339&rft_id=info:doi/10.3727%2F096368915X686841&rft_id=info%3Apmid%2F25622293&rft.externalDocID=25622293
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0963-6897&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0963-6897&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0963-6897&client=summon