Exploring the mechanism of tetramethylpyrazine in the treatment of osteoarthritis based on network pharmacology

• Published in: Frontiers in chemistry Vol. 12; p. 1415390
• Main Authors: Li, Juncen, Song, Daiying, Li, Bohui, Wang, Yajie, Sun, Huilin, Li, Qinglin, Lin, Xiangming, Wang, Di, Zhou, Guangdong, Liu, Yu
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 30.10.2024
• Subjects: bioinformatics analysis; Chemistry; molecular docking simulation; network pharmacology; osteoarthritis; Tetramethylpyrazine; molecular docking simulation; network pharmacology; Tetramethylpyrazine; bioinformatics analysis; osteoarthritis

Osteoarthritis (OA) is the most common joint disease, which mainly damages articular cartilage and involves the whole joint tissue. It has the characteristics of long course, repeated symptoms and high disability rate, and the incidence trend is gradually increasing. Tetramethylpyrazine (TMP) is the...