Limonene formulation exhibited potential application in the control of mycelial growth and deoxynivalenol production in Fusarium graminearum
Preventing grain from fungi and subsequent mycotoxins contamination has attracted notable attention. Present study demonstrated the limonene-formulated product Wetcit ® , might be a biocontrol agent and potential alternative to synthetic fungicides to control Fusarium graminearum growth and deoxyniv...
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| Published in | Frontiers in microbiology Vol. 14; p. 1161244 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
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Frontiers Media S.A
23.03.2023
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| Abstract | Preventing grain from fungi and subsequent mycotoxins contamination has attracted notable attention. Present study demonstrated the limonene-formulated product Wetcit
®
, might be a biocontrol agent and potential alternative to synthetic fungicides to control
Fusarium graminearum
growth and deoxynivalenol (DON) production. The limonene formulation exhibited antifungal activity against
F. graminearum
with the EC
50
at 1.40 μl/ml, electron microscopy and staining analysis showed limonene formulation could significantly decrease the quantity, length and septa of conidia, caused hyphal break and shrink, damaged the structures of cell membrane, cell wall, vacuoles and organelles in the hypha. Further study revealed the antifungal and antitoxic mechanism of limonene formulation against
F. graminearum
, limonene formulation significantly inhibited the toxisome and DON formation, was associated with the down-regulation of trichothecenes biosynthesis genes expression and many energy metabolism pathways as well as the inhibition of lipid droplets, the disturbed energy homeostasis and intracellular structures might ultimately inhibit fungal growth and DON production. In addition, limonene formulation enhanced the antifungal activity of triazole fungicides tebuconazole and mefentrifluconazole against
F. graminearum
, indicated limonene formulation has valuable potential as a bio-alternative fungicide and eco-friendly compound preparation for the effective management of
F. graminearum
and DON contamination in agriculture. |
|---|---|
| AbstractList | Preventing grain from fungi and subsequent mycotoxins contamination has attracted notable attention. Present study demonstrated the limonene-formulated product Wetcit
®
, might be a biocontrol agent and potential alternative to synthetic fungicides to control
Fusarium graminearum
growth and deoxynivalenol (DON) production. The limonene formulation exhibited antifungal activity against
F. graminearum
with the EC
50
at 1.40 μl/ml, electron microscopy and staining analysis showed limonene formulation could significantly decrease the quantity, length and septa of conidia, caused hyphal break and shrink, damaged the structures of cell membrane, cell wall, vacuoles and organelles in the hypha. Further study revealed the antifungal and antitoxic mechanism of limonene formulation against
F. graminearum
, limonene formulation significantly inhibited the toxisome and DON formation, was associated with the down-regulation of trichothecenes biosynthesis genes expression and many energy metabolism pathways as well as the inhibition of lipid droplets, the disturbed energy homeostasis and intracellular structures might ultimately inhibit fungal growth and DON production. In addition, limonene formulation enhanced the antifungal activity of triazole fungicides tebuconazole and mefentrifluconazole against
F. graminearum
, indicated limonene formulation has valuable potential as a bio-alternative fungicide and eco-friendly compound preparation for the effective management of
F. graminearum
and DON contamination in agriculture. Preventing grain from fungi and subsequent mycotoxins contamination has attracted notable attention. Present study demonstrated the limonene-formulated product Wetcit , might be a biocontrol agent and potential alternative to synthetic fungicides to control growth and deoxynivalenol (DON) production. The limonene formulation exhibited antifungal activity against with the EC at 1.40 μl/ml, electron microscopy and staining analysis showed limonene formulation could significantly decrease the quantity, length and septa of conidia, caused hyphal break and shrink, damaged the structures of cell membrane, cell wall, vacuoles and organelles in the hypha. Further study revealed the antifungal and antitoxic mechanism of limonene formulation against , limonene formulation significantly inhibited the toxisome and DON formation, was associated with the down-regulation of trichothecenes biosynthesis genes expression and many energy metabolism pathways as well as the inhibition of lipid droplets, the disturbed energy homeostasis and intracellular structures might ultimately inhibit fungal growth and DON production. In addition, limonene formulation enhanced the antifungal activity of triazole fungicides tebuconazole and mefentrifluconazole against , indicated limonene formulation has valuable potential as a bio-alternative fungicide and eco-friendly compound preparation for the effective management of and DON contamination in agriculture. Preventing grain from fungi and subsequent mycotoxins contamination has attracted notable attention. Present study demonstrated the limonene-formulated product Wetcit®, might be a biocontrol agent and potential alternative to synthetic fungicides to control Fusarium graminearum growth and deoxynivalenol (DON) production. The limonene formulation exhibited antifungal activity against F. graminearum with the EC50 at 1.40 μl/ml, electron microscopy and staining analysis showed limonene formulation could significantly decrease the quantity, length and septa of conidia, caused hyphal break and shrink, damaged the structures of cell membrane, cell wall, vacuoles and organelles in the hypha. Further study revealed the antifungal and antitoxic mechanism of limonene formulation against F. graminearum, limonene formulation significantly inhibited the toxisome and DON formation, was associated with the down-regulation of trichothecenes biosynthesis genes expression and many energy metabolism pathways as well as the inhibition of lipid droplets, the disturbed energy homeostasis and intracellular structures might ultimately inhibit fungal growth and DON production. In addition, limonene formulation enhanced the antifungal activity of triazole fungicides tebuconazole and mefentrifluconazole against F. graminearum, indicated limonene formulation has valuable potential as a bio-alternative fungicide and eco-friendly compound preparation for the effective management of F. graminearum and DON contamination in agriculture. Preventing grain from fungi and subsequent mycotoxins contamination has attracted notable attention. Present study demonstrated the limonene-formulated product Wetcit®, might be a biocontrol agent and potential alternative to synthetic fungicides to control Fusarium graminearum growth and deoxynivalenol (DON) production. The limonene formulation exhibited antifungal activity against F. graminearum with the EC50 at 1.40 μl/ml, electron microscopy and staining analysis showed limonene formulation could significantly decrease the quantity, length and septa of conidia, caused hyphal break and shrink, damaged the structures of cell membrane, cell wall, vacuoles and organelles in the hypha. Further study revealed the antifungal and antitoxic mechanism of limonene formulation against F. graminearum, limonene formulation significantly inhibited the toxisome and DON formation, was associated with the down-regulation of trichothecenes biosynthesis genes expression and many energy metabolism pathways as well as the inhibition of lipid droplets, the disturbed energy homeostasis and intracellular structures might ultimately inhibit fungal growth and DON production. In addition, limonene formulation enhanced the antifungal activity of triazole fungicides tebuconazole and mefentrifluconazole against F. graminearum, indicated limonene formulation has valuable potential as a bio-alternative fungicide and eco-friendly compound preparation for the effective management of F. graminearum and DON contamination in agriculture.Preventing grain from fungi and subsequent mycotoxins contamination has attracted notable attention. Present study demonstrated the limonene-formulated product Wetcit®, might be a biocontrol agent and potential alternative to synthetic fungicides to control Fusarium graminearum growth and deoxynivalenol (DON) production. The limonene formulation exhibited antifungal activity against F. graminearum with the EC50 at 1.40 μl/ml, electron microscopy and staining analysis showed limonene formulation could significantly decrease the quantity, length and septa of conidia, caused hyphal break and shrink, damaged the structures of cell membrane, cell wall, vacuoles and organelles in the hypha. Further study revealed the antifungal and antitoxic mechanism of limonene formulation against F. graminearum, limonene formulation significantly inhibited the toxisome and DON formation, was associated with the down-regulation of trichothecenes biosynthesis genes expression and many energy metabolism pathways as well as the inhibition of lipid droplets, the disturbed energy homeostasis and intracellular structures might ultimately inhibit fungal growth and DON production. In addition, limonene formulation enhanced the antifungal activity of triazole fungicides tebuconazole and mefentrifluconazole against F. graminearum, indicated limonene formulation has valuable potential as a bio-alternative fungicide and eco-friendly compound preparation for the effective management of F. graminearum and DON contamination in agriculture. |
| Author | Luo, Yuqin Jian, Yunqing Yin, Yanni Chen, Xia Ma, Haiqin Jiang, Jinhua Zhang, Changpeng |
| AuthorAffiliation | 2 State Key Laboratory of Rice Biology, Institute of Biotechnology, Zhejiang University , Hangzhou, Zhejiang , China 3 Oro Agri International Ltd , Fresno, CA , United States 1 State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Key Laboratory for Pesticide Residue Detection of Ministry of Agriculture, Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences , Hangzhou, Zhejiang , China |
| AuthorAffiliation_xml | – name: 3 Oro Agri International Ltd , Fresno, CA , United States – name: 1 State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Key Laboratory for Pesticide Residue Detection of Ministry of Agriculture, Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences , Hangzhou, Zhejiang , China – name: 2 State Key Laboratory of Rice Biology, Institute of Biotechnology, Zhejiang University , Hangzhou, Zhejiang , China |
| Author_xml | – sequence: 1 givenname: Yunqing surname: Jian fullname: Jian, Yunqing – sequence: 2 givenname: Xia surname: Chen fullname: Chen, Xia – sequence: 3 givenname: Haiqin surname: Ma fullname: Ma, Haiqin – sequence: 4 givenname: Changpeng surname: Zhang fullname: Zhang, Changpeng – sequence: 5 givenname: Yuqin surname: Luo fullname: Luo, Yuqin – sequence: 6 givenname: Jinhua surname: Jiang fullname: Jiang, Jinhua – sequence: 7 givenname: Yanni surname: Yin fullname: Yin, Yanni |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/37125209$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1139/B08-052 10.1016/j.fct.2018.07.052 10.3389/fmicb.2021.768414 10.2174/1389201022666210812115233 10.1271/bbb.50571 10.1021/acs.jafc.6b04847 10.1016/j.foodchem.2022.132479 10.1111/1462-2920.12334 10.1371/journal.pone.0131733 10.1080/14786419.2020.1802267 10.24425/jppr.2020.132202 10.1007/s00294-003-0379-2 10.3390/molecules25112598 10.1146/annurev-phyto-082718-100318 10.1080/0972060X.2022.2090283 10.1016/j.jhazmat.2021.125663 10.3390/molecules24020311 10.1002/jsfa.6225 10.1016/j.scitotenv.2020.140611 10.3390/pathogens9010023 10.1016/j.envpol.2019.03.031 10.3390/jof8010012 10.1080/10408398.2017.1384716 10.1016/j.foodcont.2018.07.030 10.1080/10408398.2019.1571479 10.1007/s10340-016-0827-7 10.1016/j.jhazmat.2021.126303 10.1094/PHYTO-98-9-0999 10.1080/19440049.2018.1520397 10.1046/j.1365-2818.2000.00708.x 10.3389/fmicb.2021.633714 10.1038/s41580-018-0085-z 10.1111/nph.13374 10.1016/j.mimet.2003.10.018 10.3389/fmicb.2015.00892 10.1016/j.cropro.2016.10.002 10.1016/j.lwt.2016.02.005 10.1016/j.jep.2020.113135 10.1016/j.pestbp.2012.03.004 10.3390/foods10092016 10.1111/j.1364-3703.2011.00783.x 10.1146/annurev-phyto-080508-081737 10.1006/meth.2001.1262 10.1002/ptr.7281 10.1094/PDIS.1999.83.10.954 10.1371/journal.pone.0063077 10.1080/02652030500058403 10.3390/toxins12090562 10.3389/fmicb.2021.762844 10.1016/j.scitotenv.2021.151192 10.1111/jfbc.13566 10.1128/mr.54.3.266-292.1990 |
| ContentType | Journal Article |
| Copyright | Copyright © 2023 Jian, Chen, Ma, Zhang, Luo, Jiang and Yin. Copyright © 2023 Jian, Chen, Ma, Zhang, Luo, Jiang and Yin. 2023 Jian, Chen, Ma, Zhang, Luo, Jiang and Yin |
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| Keywords | DON production Fusarium graminearum antifungal activity limonene formulation antitoxic effect |
| Language | English |
| License | Copyright © 2023 Jian, Chen, Ma, Zhang, Luo, Jiang and Yin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
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| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Edited by: Mehdi Razzaghi-Abyaneh, Pasteur Institute of Iran (PII), Iran These authors have contributed equally to this work This article was submitted to Food Microbiology, a section of the journal Frontiers in Microbiology Reviewed by: Elsherbiny A. Elsherbiny, Mansoura University, Egypt; Severino Zara, University of Sassari, Italy |
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| References | Ravichandran (ref42) 2018; 120 Akhavan-Mahdavi (ref1) 2022; 384 Marei (ref30) 2012; 103 Jenczmionka (ref16) 2003; 43 Lu (ref25) 2022; 806 Nidhi (ref34) 2020; 262 Rocha (ref43) 2005; 22 Cai (ref4) 2022; 36 Mishra (ref32) 2020; 60 Das (ref6) 2021; 12 Chen (ref5) 2019; 57 Gao (ref13) 2021; 12 Dassanayake (ref7) 2021; 10 Ibáñez (ref15) 2020; 25 Ma (ref27) 2015; 10 Sugita-Konishi (ref45) 2006; 70 Wang (ref48) 2019; 39 Krzyśko-Łupicka (ref21) 2019; 24 Kimura (ref19) 2004; 56 Kalagatur (ref18) 2015; 6 (ref37) 2018 Tian (ref47) 2021; 415 Ferreira (ref10) 2018; 35 Xu (ref50) 2009; 47 Yun (ref51) 2015; 207 Zhang (ref54) 2020; 742 Gadban (ref12) 2020; 60 Livak (ref24) 2001; 25 Luchesi (ref26) 2022; 36 Lee (ref22) 2017; 65 Dean (ref8) 2012; 13 Naveen Kumar (ref33) 2016; 69 Punetha (ref41) 2022; 23 Fischer-Parton (ref11) 2000; 198 Kalagatur (ref17) 2018; 94 Paul (ref39) 2008; 98 Yun (ref52) 2014; 16 Dweba (ref9) 2017; 91 Klionsky (ref20) 1990; 54 Bulkan (ref3) 2021; 8 Perczak (ref40) 2019; 9 Niedobová (ref35) 2019; 249 Harris (ref14) 1999; 83 Anandakumar (ref2) 2021; 45 Man (ref29) 2021; 418 Xiang (ref49) 2020; 12 Mahato (ref28) 2019; 59 Zhang (ref53) 2022; 25 Paranidharan (ref38) 2008; 86 Menke (ref31) 2013; 8 Streit (ref44) 2013; 93 Tak (ref46) 2017; 90 Li (ref23) 2021; 12 Olzmann (ref36) 2019; 20 |
| References_xml | – volume: 86 start-page: 1168 year: 2008 ident: ref38 article-title: Resistance-related metabolites in wheat against Fusarium graminearum and the virulence factor deoxynivalenol (DON) publication-title: Botany doi: 10.1139/B08-052 – volume: 120 start-page: 668 year: 2018 ident: ref42 article-title: Review of toxicological assessment of d-limonene, a food and cosmetics additive publication-title: Food Chem. Toxicol. doi: 10.1016/j.fct.2018.07.052 – volume: 12 start-page: 768414 year: 2021 ident: ref6 article-title: Nanoencapsulation-based edible coating of essential oils as a novel green strategy against fungal spoilage, mycotoxin contamination, and quality deterioration of stored fruits: an overview publication-title: Front. Microbiol. doi: 10.3389/fmicb.2021.768414 – volume: 23 start-page: 904 year: 2022 ident: ref41 article-title: Recent advancements in green synthesis of nanoparticles for improvement of bioactivities: a review publication-title: Curr. Pharm. Biotechno. doi: 10.2174/1389201022666210812115233 – volume: 70 start-page: 1764 year: 2006 ident: ref45 article-title: Effect of cooking process on the deoxynivalenol content and its subsequent cytotoxicity in wheat products publication-title: Biosci. Biotech. Bioch. doi: 10.1271/bbb.50571 – volume: 65 start-page: 7034 year: 2017 ident: ref22 article-title: Worldwide occurrence of mycotoxins in cereals and cereal-derived food products: public health perspectives of their co-occurrence publication-title: J. Agric. Food Chem. doi: 10.1021/acs.jafc.6b04847 – volume: 384 start-page: 132479 year: 2022 ident: ref1 article-title: Nanodelivery systems for d-limonene; techniques and applications publication-title: Food Chem. doi: 10.1016/j.foodchem.2022.132479 – volume: 16 start-page: 2023 year: 2014 ident: ref52 article-title: The MAPKK FgMkk1 of Fusarium graminearum regulates vegetative differentiation, multiple stress response, and virulence via the cell wall integrity and high-osmolarity glycerol signaling pathways: function of FgMkk1 in F. graminearum publication-title: Environ. Microbiol. doi: 10.1111/1462-2920.12334 – volume: 39 start-page: 23 year: 2019 ident: ref48 article-title: Synergism of essential oil d-limonene with imidacloprid and its mechanisms publication-title: China Plant Prot. – volume: 10 start-page: e0131733 year: 2015 ident: ref27 article-title: Interference and mechanism of dill seed essential oil and contribution of carvone and limonene in preventing Sclerotinia rot of rapeseed publication-title: PLoS One doi: 10.1371/journal.pone.0131733 – volume: 36 start-page: 849 year: 2022 ident: ref26 article-title: Chemical composition, antifungal and antioxidant activity of essential oils from Baccharis dracunculifolia and Pogostemon cablin against Fusarium graminearum publication-title: Nat. Prod. Res. doi: 10.1080/14786419.2020.1802267 – volume: 60 start-page: 41 year: 2020 ident: ref12 article-title: Combinations of Tagetes filifolia lag. Essential oil with chemical fungicides to control Colletotrichum truncatum and their effects on the biocontrol agent Trichoderma harzianum publication-title: J. Plant Prot. Res. doi: 10.24425/jppr.2020.132202 – volume: 43 start-page: 87 year: 2003 ident: ref16 article-title: Mating, conidiation and pathogenicity of Fusarium graminearum, the main causal agent of the head-blight disease of wheat, are regulated by the MAP kinase gpmk1 publication-title: Curr. Genet. doi: 10.1007/s00294-003-0379-2 – volume: 25 start-page: 2598 year: 2020 ident: ref15 article-title: Encapsulated limonene: a pleasant lemon-like aroma with promising application in the agri-food industry. A review publication-title: Molecules. doi: 10.3390/molecules25112598 – volume: 57 start-page: 15 year: 2019 ident: ref5 article-title: Fusarium graminearum trichothecene mycotoxins: biosynthesis, regulation, and management publication-title: Annu. Rev. Phytopathol. doi: 10.1146/annurev-phyto-082718-100318 – year: 2018 ident: ref37 – volume: 25 start-page: 536 year: 2022 ident: ref53 article-title: The antifungal activity and action mechanism of lemongrass (Cymbopogon flexuosus) essential oil against Fusarium avenaceum publication-title: J. Essent. Oil Bear. Pl. doi: 10.1080/0972060X.2022.2090283 – volume: 415 start-page: 125663 year: 2021 ident: ref47 article-title: Effect of plant-based compounds on the antifungal and antiaflatoxigenic efficiency of strobilurins against aspergillus flavus publication-title: J. Hazard. Mater. doi: 10.1016/j.jhazmat.2021.125663 – volume: 24 start-page: 311 year: 2019 ident: ref21 article-title: Comparison of the fungistatic activity of selected essential oils relative to Fusarium graminearum isolates publication-title: Molecules doi: 10.3390/molecules24020311 – volume: 93 start-page: 2892 year: 2013 ident: ref44 article-title: Mycotoxin occurrence in feed and feed raw materials worldwide: long-term analysis with special focus on Europe and Asia: mycotoxin occurrence in feed and feed raw materials worldwide publication-title: J. Sci. Food Agr. doi: 10.1002/jsfa.6225 – volume: 742 start-page: 140611 year: 2020 ident: ref54 article-title: Ecotoxicology of strobilurin fungicides publication-title: Sci. Total Environ. doi: 10.1016/j.scitotenv.2020.140611 – volume: 9 start-page: 23 year: 2019 ident: ref40 article-title: The inhibitory potential of selected essential oils on Fusarium spp. growth and mycotoxins biosynthesis in maize seeds publication-title: Pathogens doi: 10.3390/pathogens9010023 – volume: 249 start-page: 338 year: 2019 ident: ref35 article-title: Synergistic effects of glyphosate formulation herbicide and tank-mixing adjuvants on Pardosa spiders publication-title: Environ. Pollut. doi: 10.1016/j.envpol.2019.03.031 – volume: 8 start-page: 12 year: 2021 ident: ref3 article-title: Enhancing or inhibitory effect of fruit or vegetable bioactive compound on Aspergillus niger and A. oryzae publication-title: J. Fungi doi: 10.3390/jof8010012 – volume: 59 start-page: 611 year: 2019 ident: ref28 article-title: Citrus essential oils: extraction, authentication and application in food preservation publication-title: Crit. Rev. Food Sci. Nutr. doi: 10.1080/10408398.2017.1384716 – volume: 94 start-page: 276 year: 2018 ident: ref17 article-title: Discrete and combined effects of Ylang-Ylang (Cananga odorata) essential oil and gamma irradiation on growth and mycotoxins production by Fusarium graminearum in maize publication-title: Food Control doi: 10.1016/j.foodcont.2018.07.030 – volume: 60 start-page: 1346 year: 2020 ident: ref32 article-title: Global occurrence of deoxynivalenol in food commodities and exposure risk assessment in humans in the last decade: a survey publication-title: Crit. Rev. Food Sci. Nutr. doi: 10.1080/10408398.2019.1571479 – volume: 90 start-page: 735 year: 2017 ident: ref46 article-title: Synergistic interactions among the major constituents of lemongrass essential oil against larvae and an ovarian cell line of the cabbage looper publication-title: Trichoplusia ni. J. Pest Sci. doi: 10.1007/s10340-016-0827-7 – volume: 418 start-page: 126303 year: 2021 ident: ref29 article-title: Degradation of difenoconazole in water and soil: kinetics, degradation pathways, transformation products identification and ecotoxicity assessment publication-title: J. Hazard. Mater. doi: 10.1016/j.jhazmat.2021.126303 – volume: 98 start-page: 999 year: 2008 ident: ref39 article-title: Efficacy of triazole-based fungicides for fusarium head blight and deoxynivalenol control in wheat: a multivariate meta-analysis publication-title: Phytopathology doi: 10.1094/PHYTO-98-9-0999 – volume: 35 start-page: 2168 year: 2018 ident: ref10 article-title: Effect of Zingiber officinale roscoe essential oil in fungus control and deoxynivalenol production of fusarium graminearum Schwabe in vitro publication-title: Food Addit. Contam. Part A doi: 10.1080/19440049.2018.1520397 – volume: 198 start-page: 246 year: 2000 ident: ref11 article-title: Confocal microscopy of FM4-64 as a tool for analysing endocytosis and vesicle trafficking in living fungal hyphae publication-title: J. Microsc. doi: 10.1046/j.1365-2818.2000.00708.x – volume: 12 start-page: 633714 year: 2021 ident: ref23 article-title: Antifungal activity of essential oil from Zanthoxylum armatum DC. On aspergillus flavus and aflatoxins in stored platycladi semen publication-title: Front. Microbiol. doi: 10.3389/fmicb.2021.633714 – volume: 20 start-page: 137 year: 2019 ident: ref36 article-title: Dynamics and functions of lipid droplets publication-title: Nat. Rev. Mol. Cell Bio. doi: 10.1038/s41580-018-0085-z – volume: 207 start-page: 119 year: 2015 ident: ref51 article-title: Functional analysis of the fusarium graminearum phosphatome publication-title: New Phytol. doi: 10.1111/nph.13374 – volume: 56 start-page: 331 year: 2004 ident: ref19 article-title: Rapid estimation of lipids in oleaginous fungi and yeasts using Nile red fluorescence publication-title: J. Microbiol. Meth. doi: 10.1016/j.mimet.2003.10.018 – volume: 6 start-page: 892 year: 2015 ident: ref18 article-title: Antagonistic activity of Ocimum sanctum L. essential oil on growth and zearalenone production by Fusarium graminearum in maize grains publication-title: Front. Microbiol. doi: 10.3389/fmicb.2015.00892 – volume: 91 start-page: 114 year: 2017 ident: ref9 article-title: Fusarium head blight of wheat: pathogenesis and control strategies publication-title: Crop Prot. doi: 10.1016/j.cropro.2016.10.002 – volume: 69 start-page: 522 year: 2016 ident: ref33 article-title: Role of Curcuma longa L. essential oil in controlling the growth and zearalenone production of Fusarium graminearum publication-title: LWT-Food Sci. Technol. doi: 10.1016/j.lwt.2016.02.005 – volume: 262 start-page: 113135 year: 2020 ident: ref34 article-title: Synergistic potential of Citrus aurantium L. essential oil with antibiotics against Candida albicans publication-title: J. Ethnopharmacol. doi: 10.1016/j.jep.2020.113135 – volume: 103 start-page: 56 year: 2012 ident: ref30 article-title: Comparative antifungal activities and biochemical effects of monoterpenes on plant pathogenic fungi publication-title: Pestic. Biochem. Phys. doi: 10.1016/j.pestbp.2012.03.004 – volume: 10 start-page: 2016 year: 2021 ident: ref7 article-title: Synergistic field crop pest management properties of plant-derived essential oils in combination with synthetic pesticides and bioactive molecules: a review publication-title: Foods doi: 10.3390/foods10092016 – volume: 13 start-page: 414 year: 2012 ident: ref8 article-title: The top 10 fungal pathogens in molecular plant pathology: top 10 fungal pathogens publication-title: Mol. Plant Pathol. doi: 10.1111/j.1364-3703.2011.00783.x – volume: 47 start-page: 83 year: 2009 ident: ref50 article-title: Community ecology of fungal pathogens causing wheat head blight publication-title: Annu. Rev. Phytopathol. doi: 10.1146/annurev-phyto-080508-081737 – volume: 25 start-page: 402 year: 2001 ident: ref24 article-title: Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔΔCT method publication-title: Methods doi: 10.1006/meth.2001.1262 – volume: 36 start-page: 62 year: 2022 ident: ref4 article-title: Antifungal and mycotoxin detoxification ability of essential oils: a review publication-title: Phytother. Res. doi: 10.1002/ptr.7281 – volume: 83 start-page: 954 year: 1999 ident: ref14 article-title: Possible role of trichothecene mycotoxins in virulence of Fusarium graminearum on maize publication-title: Plant Dis. doi: 10.1094/PDIS.1999.83.10.954 – volume: 8 start-page: e63077 year: 2013 ident: ref31 article-title: Cellular development associated with induced mycotoxin synthesis in the filamentous fungus Fusarium graminearum publication-title: PLoS One doi: 10.1371/journal.pone.0063077 – volume: 22 start-page: 369 year: 2005 ident: ref43 article-title: Effects of trichothecene mycotoxins on eukaryotic cells: a review publication-title: Food Addit. Contam. doi: 10.1080/02652030500058403 – volume: 12 start-page: 562 year: 2020 ident: ref49 article-title: The efficacy of composite essential oils against aflatoxigenic fungus aspergillus flavus in maize publication-title: Toxins doi: 10.3390/toxins12090562 – volume: 12 start-page: 762844 year: 2021 ident: ref13 article-title: The antioxidant guaiacol exerts fungicidal activity against fungal growth and deoxynivalenol production in Fusarium graminearum publication-title: Front. Microbiol. doi: 10.3389/fmicb.2021.762844 – volume: 806 start-page: 151192 year: 2022 ident: ref25 article-title: Structure-toxicity relationships, toxicity mechanisms and health risk assessment of food-borne modified deoxynivalenol and zearalenone: a comprehensive review publication-title: Sci. Total Environ. doi: 10.1016/j.scitotenv.2021.151192 – volume: 45 start-page: e13566 year: 2021 ident: ref2 article-title: D-limonene: a multifunctional compound with potent therapeutic effects publication-title: J. Food Biochem. doi: 10.1111/jfbc.13566 – volume: 54 start-page: 266 year: 1990 ident: ref20 article-title: The fungal vacuole: composition, function, and biogenesis publication-title: Microbiol. Rev. doi: 10.1128/mr.54.3.266-292.1990 |
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| SubjectTerms | antifungal activity antitoxic effect DON production Fusarium graminearum limonene formulation Microbiology |
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| Title | Limonene formulation exhibited potential application in the control of mycelial growth and deoxynivalenol production in Fusarium graminearum |
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