Secondary Amine Catalysis in Enzyme Design: Broadening Protein Template Diversity through Genetic Code Expansion - Williams, Thomas L.; Taily, Irshad M.; Hatton, Lewis; Berezin, Andrey A; Wu, Yi‐Lin; Moliner, Vicent; Świderek, Katarzyna; Tsai, Yu‐Hsuan; Luk, Louis Y. P. (Angewandte Chemie International Edition, 2024)
Keywords: Amines; Artificial Enzyme; Binding; Biocatalysis; Biocatalysts; Biomimetics; Catalysis; Catalytic activity; Dihydrofolate reductase; Enzymes; Fluorescence; Genetic Code; Genetic Code Expansion; Genetic diversity; Green fluorescent protein; Green Fluorescent Proteins - chemistry; Green Fluorescent Proteins - genetics; Green Fluorescent Proteins - metabolism; Hydrides; Lysine - analogs & derivatives; Lysine - chemistry; Lysine - metabolism; Nucleophiles; Nucleotides; Organocatalysis; Protein Engineering; Proteins; Proteolysis; Recycling programs; Reductases; Secondary Amine Catalysis; Stereoselectivity; Tetrahydrofolate Dehydrogenase - chemistry; Tetrahydrofolate Dehydrogenase - genetics; Tetrahydrofolate Dehydrogenase - metabolism; Artificial Enzyme; Genetic Code Expansion; Organocatalysis; Secondary Amine Catalysis; Protein Engineering