An unusual instance of leukemic infiltrate diagnosis and management of periapical tooth involvement

The clinical course of an adult patient with relapsed acute myelogenous leukemia and leukemic infiltrate periapical to the dentition is described. While the oral symptoms were indicative of pulpal disease requiring dental therapy to resolve the patient‐s complaint, roentgenographic, dental pulp test...

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Published inCancer Vol. 51; no. 9; pp. 1716 - 1719
Main Authors Peterson, Douglas E., Gerad, Henry, Williams, Lisa T.
Format Journal Article
LanguageEnglish
Published New York Wiley Subscription Services, Inc., A Wiley Company 01.05.1983
Subjects
Adult
Dental Pulp - pathology
Humans
Leukemia, Myeloid, Acute - diagnostic imaging
Leukemia, Myeloid, Acute - mortality
Male
Periapical Diseases - diagnostic imaging
Periapical Diseases - pathology
Periapical Diseases - surgery
Radiography
Recurrence
Tooth Extraction
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Abstract The clinical course of an adult patient with relapsed acute myelogenous leukemia and leukemic infiltrate periapical to the dentition is described. While the oral symptoms were indicative of pulpal disease requiring dental therapy to resolve the patient‐s complaint, roentgenographic, dental pulp testing, and histologic analysis revealed extramedullary infiltrate apical to a mandibular molar. The findings developed coincident with relapse of leukemia; the medical and dental testing described above were essential in establishing an accurate diagnosis. While most oral leukemic infiltrates affect the gingiva, in this patient the infiltrate involved periapical tissue which was not clinically observable.
AbstractList The clinical course of an adult patient with relapsed acute myelogenous leukemia and leukemic infiltrate periapical to the dentition is described. While the oral symptoms were indicative of pulpal disease requiring dental therapy to resolve the patient's complaint, roentgenographic, dental pulp testing, and histologic analysis revealed extramedullary infiltrate apical to a mandibular molar. The findings developed coincident with relapse of leukemia; the medical and dental testing described above were essential in establishing an accurate diagnosis. While most oral leukemic infiltrates affect the gingiva, in this patient the infiltrate involved periapical tissue which was not clinically observable.
Author Williams, Lisa T.
Peterson, Douglas E.
Gerad, Henry
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Cites_doi 10.1016/0030-4220(79)90099-9
10.14219/jada.archive.1971.0405
10.1001/archinte.1982.00340160131025
10.1016/0030-4220(79)90230-5
10.1016/0145-2126(77)90045-5
10.1016/0030-4220(73)90212-0
10.1182/blood.V46.1.17.17
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Snippet The clinical course of an adult patient with relapsed acute myelogenous leukemia and leukemic infiltrate periapical to the dentition is described. While the...
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SubjectTerms Adult
Dental Pulp - pathology
Humans
Leukemia, Myeloid, Acute - diagnostic imaging
Leukemia, Myeloid, Acute - mortality
Male
Periapical Diseases - diagnostic imaging
Periapical Diseases - pathology
Periapical Diseases - surgery
Radiography
Recurrence
Tooth Extraction
Title An unusual instance of leukemic infiltrate diagnosis and management of periapical tooth involvement
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