Serum Sirtuin1 level decreases in Parkinson's disease and vascular parkinsonism: A prospective observational study - Li, Yifeng; Zhang, Chengmei; Xu, Wei; Chen, Jihua; Tuo, Jia; Wen, Ying; Huang, Zhongxiong; Zeng, Rong (Clinical neurology and neurosurgery, 2023)
Keywords: Age; Basal ganglia; Biomarkers; Body mass index; Brain diseases; Central nervous system diseases; Clinical significance; Cognitive ability; Diagnostic biomarker; Enzyme-linked immunosorbent assay; Humans; Interleukin 6; Movement disorders; Neurodegenerative diseases; Neurological disorders; Neurology; Neurosurgery; Observational studies; Observational Studies as Topic; Oxidative stress; Parkinson Disease - diagnosis; Parkinson Disease, Secondary - diagnosis; Parkinson's disease; Patients; Prospective Studies; Regression analysis; Risk factors; SIRT1; SIRT1 protein; Sirtuin 1; Statistical analysis; Tumor necrosis factor-TNF; UPDRS; Vascular Diseases; Vascular parkinsonism; CRP; ChE; Parkinson's disease; IL; SIRT1; CMRGlc; Diagnostic biomarker; NAD; TNF- α; Hoehn-Yahr; PD; UPDRSIII; NMS; MMSE; TFF3; UPDRS; VP; NMSS; Vascular parkinsonism; ApoE-KO; MDS; ELISA; hcy; BMI; modified Hoehn and Yahr staging scale; C-reactive protein; tumor necrosis factor α; cholinesterase; Interleukin; cerebral glucose metabolic rate; movement disorder society; nicotinamide adenine dinucleotide; apolipoprotein E-knockout; unified Parkinson's disease rating scale III; Sirtuin1; homocysteine; Body Mass Index; non-motor symptoms; Trefoil factor 3; Non-Motor Symptoms Scale; enzyme-linked immunosorbent assay; mini-mental state examination