Centrally Produced Nitric Oxide And The Regulation Of Body Fluid And Blood Pressure Homeostases

• Published in: Clinical and experimental pharmacology & physiology Vol. 27; no. 5-6; pp. 450 - 459
• Main Authors: Kadekaro, Massako, Summy-Long, Joan Y
• Format: Journal Article
• Language: English
• Published: Melbourne, Australia Blackwell Science Pty 01.05.2000
• Subjects: angiotensin II; Animals; Blood Pressure - drug effects; Blood Pressure - physiology; Body Fluids - drug effects; Body Fluids - physiology; Brain - drug effects; Brain - physiology; drinking; Drinking Behavior - drug effects; Drinking Behavior - physiology; Enzyme Inhibitors - pharmacology; Homeostasis - drug effects; Homeostasis - physiology; Humans; Hypothalamic Hormones - metabolism; NG-nitro-L-arginine methyl ester; NG-Nitroarginine Methyl Ester - pharmacology; Nitric Oxide - physiology; oxytocin; Oxytocin - metabolism; vasopressin; Vasopressins - metabolism; Water-Electrolyte Balance

SUMMARY 1. Nitric oxide (NO) tonically inhibits the basal release of vasopressin and oxytocin into plasma. 2. Nitric oxide inhibition on vasopressin secretion is removed, while that on oxytocin is enhanced, during water deprivation, hypovolaemia, moderate osmotic stimulation and angiotensin (Ang)II....