Review of the key results from the Swedish Obese Subjects (SOS) trial – a prospective controlled intervention study of bariatric surgery

• Published in: Journal of internal medicine Vol. 273; no. 3; pp. 219 - 234
• Main Author: Sjöström, L.
• Format: Journal Article
• Language: English
• Published: England 01.03.2013
• Subjects: Adult; aged 40-64 years; bariatric surgery; Bariatric Surgery - mortality; Body Mass Index; Body Weight; cardiovascular risk-factors; Clinical Medicine; Comorbidity; Diabetes Mellitus - epidemiology; Diabetes Mellitus - prevention & control; Diabetic Angiopathies - epidemiology; Diabetic Angiopathies - surgery; Female; finnish diabetes prevention; gastric bypass-surgery; health-care use; Humans; Incidence; incidence of diabetes; intentional weight-loss; Klinisk medicin; left-ventricular mass; life-style intervention; long-term; Male; Middle Aged; mortality; myocardial infarction; Neoplasms - epidemiology; Neoplasms - prevention & control; obesity; Obesity, Morbid - epidemiology; Obesity, Morbid - surgery; randomized controlled-trial; Stroke - epidemiology; Stroke - prevention & control; stroke and cancer; Sweden - epidemiology; Treatment Outcome; Weight Loss; Sweden

Obesity is a risk factor for diabetes, cardiovascular disease events, cancer and overall mortality. Weight loss may protect against these conditions, but robust evidence for this has been lacking. The Swedish Obese Subjects (SOS) study is the first long‐term, prospective, controlled trial to provide...