PD-L1 mediated the differentiation of tumor-infiltrating CD19+ B lymphocytes and T cells in Invasive breast cancer

• Published in: Oncoimmunology Vol. 5; no. 2; p. e1075112
• Main Authors: Guan, Honggeng, Lan, Yang, Wan, Yuqiu, Wang, Qin, Wang, Cheng, Xu, Longjiang, Chen, Yongjing, Liu, Wenting, Zhang, Xueguang, Li, Yecheng, Gu, Yongping, Wang, Zemin, Xie, Fang
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 01.02.2016
• Subjects: B lymphocytes; Breast cancer; CD19; IL-10; Original Research; PD-L1; regulatory B cell; regulatory T cell; B lymphocytes; CD19; PD-L1; Breast cancer; regulatory T cell; IL-10; regulatory B cell

Accumulating evidence suggests that B cells play important roles in inhibiting the immune response in autoimmune disorders and human tumors as well as murine tumor models. In an effort to explore the role of B cells in human breast cancer etiology, we examined the presence of CD19 + B lymphocytes in...