STRA6 regulates tumor immune microenvironment and is a prognostic marker in BRAF-mutant papillary thyroid carcinoma

• Published in: Frontiers in endocrinology (Lausanne) Vol. 14; p. 1076640
• Main Authors: He, Weiman, Sun, Yijia, Ge, Jiawei, Wang, Xuejie, Lin, Bo, Yu, Shuang, Li, Yanbing, Hong, Shubin, Xiao, Haipeng
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 10.02.2023
• Subjects: BRAF mutation; Endocrinology; papillary thyroid carcinoma (PTC); prognosis; STRA6; tumor immune microenvironment; papillary thyroid carcinoma (PTC); tumor immune microenvironment; prognosis; BRAF mutation; STRA6

BRAF mutation is one of the most common genetic alterations contributing to the initiation and progression of papillary thyroid carcinoma (PTC). However, the prognostic value of BRAF mutation for PTC is limited. Novel markers are needed to identify BRAF-mutant patients with poor prognosis. Transcrip...