Occurrence of mcr-1 and mcr-2 colistin resistance genes in porcine Escherichia coli isolates (2010–2020) and genomic characterization of mcr-2-positive E. coli

• Published in: Frontiers in microbiology Vol. 13; p. 1076315
• Main Authors: Ewers, Christa, Göpel, Lisa, Prenger-Berninghoff, Ellen, Semmler, Torsten, Kerner, Katharina, Bauerfeind, Rolf
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 09.12.2022
• Subjects: Escherichia coli; mcr-2; Microbiology; mobile colistin resistance; pathotype; plasmid; swine; IncP; swine; IncX4; pathotype; Escherichia coli; mobile colistin resistance; plasmid; mcr-2

The global emergence of plasmid-mediated colistin resistance is threatening the efficacy of colistin as one of the last treatment options against multi-drug resistant Gram-negative bacteria. To date, ten -genes ( to ) were reported. While has disseminated globally, the occurrence of was reported sca...