A Membrane-Bound Biosensor Visualizes Shear Stress-Induced Inhomogeneous Alteration of Cell Membrane Tension

• Published in: iScience Vol. 7; pp. 180 - 190
• Main Authors: Li, Wang, Yu, Xinlei, Xie, Fei, Zhang, Baohong, Shao, Shuai, Geng, Chunyang, Aziz, Aziz Ur Rehman, Liao, Xiaoling, Liu, Bo
• Format: Journal Article
• Language: English
• Published: United States Elsevier 28.09.2018
• Subjects: Membrane Architecture; Biophysics; Molecular Biology; Sensor

Cell membrane is the first medium from where a cell senses and responds to external stress stimuli. Exploring the tension changes in cell membrane will help us to understand intracellular force transmission. Here, a biosensor (named MSS) based on fluorescence resonance energy transfer is developed t...