Severe atopic dermatitis is characterized by selective expansion of circulating TH2/TC2 and TH22/TC22, but not TH17/TC17, cells within the skin-homing T-cell population - Czarnowicki, Tali; Gonzalez, Juana; Shemer, Avner; Malajian, Dana; Xu, Hui; Zheng, Xiuzhong; Khattri, Saakshi; Gilleaudeau, Patricia; Sullivan-Whalen, Mary; Suárez-Fariñas, Mayte; Krueger, James G.; Guttman-Yassky, Emma (Journal of allergy and clinical immunology, 2015)
Keywords: Adolescent; Adult; Age; Aged; Alzheimer's disease; Antigens, Differentiation, T-Lymphocyte - metabolism; Atopic dermatitis; CD8-Positive T-Lymphocytes - immunology; Cell Movement; Cells, Cultured; cutaneous lymphocyte antigen; Cytokines; Dementia; Dermatitis, Atopic - immunology; Disease Progression; Expansion; Female; Humans; IFN-γ; IL-13; IL-22; Immunophenotyping; Interleukin-17 - metabolism; Interleukin-22; Interleukins - metabolism; Lymphocytes; Male; Membrane Glycoproteins - metabolism; Middle Aged; Population; Skin - immunology; skin infections; Staphylococcus infections; Studies; T cell; T-Lymphocyte Subsets - immunology; Th17 Cells - immunology; Th2 Cells - immunology; Young Adult; MFI; IFN-γ; AD; Atopic dermatitis; cutaneous lymphocyte antigen; PMA; T cell; skin infections; ICS; CLA; IL-13; IL-22