Neutropenia after the coadministration of clozapine and nirmatrelvir-ritonavir in a patient with SARS-CoV-2 infection: A case report with a literature review

• Published in: Frontiers in psychiatry Vol. 13; p. 1096006
• Main Authors: Liu, Chun-I, Goh, Kah Kheng, Chen, Chun-Hsin
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 21.12.2022
• Subjects: clozapine; drug interactions; drug-related side effects and adverse reactions; neutropenia; Psychiatry; SARS-CoV-2; clozapine; neutropenia; SARS-CoV-2; drug interactions; drug-related side effects and adverse reactions

Schizophrenia is considered one of the major risk factors for mortality from SARS-CoV-2 infection. Early antiviral treatment is important to decrease the risk of mortality. Currently, Paxlovid (nirmatrelvir-ritonavir) has been widely used in SARS-CoV-2 patients with risk factors. However, drug-drug...