Pituitary miRNAs target GHRHR splice variants to regulate GH synthesis by mediating different intracellular signalling pathways

• Published in: RNA biology Vol. 17; no. 12; pp. 1754 - 1766
• Main Authors: Cheng, Yunyun, Chen, Ting, Song, Jie, Teng, Zhaohui, Wang, Chunli, Wang, Siyao, Lu, Guanhong, Feng, Tianqi, Qi, Qien, Xi, Qianyun, Liu, Songcai, Hao, Linlin, Zhang, Yongliang
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 01.12.2020
• Subjects: GHRHR; growth hormone synthesis; miRNA; pituitary; Research Paper; splice variants; pituitary; splice variants; GHRHR; miRNA; growth hormone synthesis

Growth hormone (GH), whose synthesis and release are mainly regulated by intracellular signals mediated by growth hormone-releasing hormone receptor (GHRHR), is one of the major pituitary hormones and critical regulators of organism growth, metabolism, and immunoregulation. Pig GHRHR splice variants...