Comparison of the mucosal and systemic antibody responses in Covid-19 recovered patients with one dose of mRNA vaccine and unexposed subjects with three doses of mRNA vaccines

• Published in: Frontiers in immunology Vol. 14; p. 1127401
• Main Authors: Liu, Shaojun, Tsun, Joseph G. S., Fung, Genevieve P. G., Lui, Grace C. Y., Chan, Kathy Y. Y., Chan, Paul K. S., Chan, Renee W. Y.
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 30.01.2023
• Subjects: Antibodies, Neutralizing; Antibody Formation; BNT162 Vaccine - immunology; COVID-19 - prevention & control; Humans; hybrid immunity; Immunity, Mucosal; Immunization, Secondary; Immunoglobulin A; Immunoglobulin G; Immunology; longitudinal study; mRNA vaccine; mRNA Vaccines - immunology; mucosal antibody; Prospective Studies; SARS – CoV – 2; SARS – CoV – 2; longitudinal study; hybrid immunity; mucosal antibody; mRNA vaccine

Immunity acquired from natural SARS-CoV-2 infection and vaccine wanes overtime. This longitudinal prospective study compared the effect of a booster vaccine (BNT162b2) in inducing the mucosal (nasal) and serological antibody between Covid-19 recovered patients and healthy unexposed subjects with two...