Controlled oxygen therapy and carbon dioxide retention during exacerbations of chronic obstructive pulmonary disease

• Published in: The Lancet (British edition) Vol. 357; no. 9255; pp. 526 - 528
• Main Authors: Moloney, Edward D, Kiely, John L, McNicholas, Walter T
• Format: Journal Article
• Language: English
• Published: London Elsevier Ltd 17.02.2001; Lancet; Elsevier Limited
• Subjects: Aged; Biological and medical sciences; Carbon dioxide; Carbon Dioxide - blood; Chronic obstructive pulmonary disease; Chronic obstructive pulmonary disease, asthma; Female; Humans; Hypercapnia - etiology; Lung Diseases, Obstructive - blood; Lung Diseases, Obstructive - complications; Lung Diseases, Obstructive - therapy; Male; Medical sciences; Oxygen; Oxygen - adverse effects; Oxygen - therapeutic use; Pneumology; Prospective Studies; Respiratory diseases; Respiratory therapy; Retention; Risk Assessment; Human; Lung disease; Corticosteroid; Respiratory disease; Bronchodilator; Carbon dioxide; Retention; Hypercapnia; Oxygen addition; Antibiotic; Hypoxemia; Bronchus disease; Obstructive pulmonary disease

Hypoxaemic patients with exacerbations of chronic obstructive pulmonary disease (COPD) are at some risk of carbon dioxide (CO 2) retention during oxygen therapy. We quantified the risk of CO 2 retention with oxygen therapy in COPD in 24 consecutive patients presenting to the accident and emergency d...