m5C regulator-mediated modification patterns and tumor microenvironment infiltration characterization in colorectal cancer: One step closer to precision medicine

• Published in: Frontiers in immunology Vol. 13; p. 1049435
• Main Authors: Chen, Baoxiang, Xi, Yiqing, Zhao, Jianhong, Hong, Yuntian, Tian, Shunhua, Zhai, Xiang, Chen, Quanjiao, Ren, Xianghai, Fan, Lifang, Xie, Xiaoyu, Jiang, Congqing
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 01.12.2022
• Subjects: 5-methylcytosine; colorectal cancer; Colorectal Neoplasms - genetics; Humans; immune infiltrates; Immunology; Immunotherapy; Molecular Targeted Therapy; Precision Medicine; RNA methylation; tumor microenvironment; Tumor Microenvironment - genetics; 5-methylcytosine; precision medicine; colorectal cancer; tumor microenvironment; immune infiltrates; RNA methylation

The RNA modification 5-methylcytosine (m5C) is one of the most prevalent post-transcriptional modifications, with increasing evidence demonstrating its extensive involvement in the tumorigenesis and progression of various cancers. Colorectal cancer (CRC) is the third most common cancer and second le...