Acorane sesquiterpenes from the deep-sea derived Penicillium bilaiae fungus with anti-neuroinflammatory effects

• Published in: Frontiers in chemistry Vol. 10; p. 1036212
• Main Authors: Zhang, Wenfang, Meng, Qingyu, Wu, Jingshuai, Cheng, Wei, Liu, Dong, Huang, Jian, Fan, Aili, Xu, Jing, Lin, Wenhan
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 23.11.2022
• Subjects: anti-neuroinflammation; bilaiaeacorenols A–R; Chemistry; fungus; Penicillium bilaiae; sesquiterpene; structure elucidation; Penicillium bilaiae; bilaiaeacorenols A–R; sesquiterpene; structure elucidation; fungus; anti-neuroinflammation

Acorane-type sesquiterpenes comprise a unique class of natural products with a range of pharmaceutical effects. Genome sequencing and gene annotation, along with qRT-PCR detection, demonstrate that the deep-sea derived Penicillium bilaiae F-28 fungus shows potential to produce acorane sesquiterpenes...