Detection of mutant KRAS and TP53 DNA in circulating exosomes from healthy individuals and patients with pancreatic cancer - Yang, Sujuan; Che, Sara P. Y.; Kurywchak, Paul; Tavormina, Jena L.; Gansmo, Liv B.; Correa de Sampaio, Pedro; Tachezy, Michael; Bockhorn, Maximilian; Gebauer, Florian; Haltom, Amanda R.; Melo, Sonia A.; LeBleu, Valerie S.; et al. (Cancer biology & therapy, 2017)
Keywords: Case-Control Studies; Cell Line, Tumor; Circulating exosomal DNA; digital PCR; DNA - blood; DNA - genetics; DNA, Neoplasm - blood; DNA, Neoplasm - genetics; exosome; Exosomes - genetics; Humans; KRAS; liquid biopsy; Mutation; pancreatic cancer; Pancreatic Neoplasms - blood; Pancreatic Neoplasms - genetics; Pancreatic Neoplasms - pathology; Polymerase Chain Reaction - methods; Proto-Oncogene Proteins p21(ras) - genetics; Research Paper; TP53; Tumor Suppressor Protein p53 - genetics; pancreatic cancer; Circulating exosomal DNA; digital PCR; KRAS; TP53; exosome; liquid biopsy