A novel mRNA vaccine, SYS6006, against SARS-CoV-2

• Published in: Frontiers in immunology Vol. 13; p. 1051576
• Main Authors: Xu, Ke, Lei, Wenwen, Kang, Bin, Yang, Hanyu, Wang, Yajuan, Lu, Yanli, Lv, Lu, Sun, Yufei, Zhang, Jing, Wang, Xiaolin, Yang, Mengjie, Dan, Mo, Wu, Guizhen
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 05.01.2023
• Subjects: Animals; COVID-19 - prevention & control; Immunization; Immunology; Mice; Mice, Transgenic; mRNA vaccine; neutralizing antibody; Omicron variant; SARS-CoV-2; spike protein; T cell immunity; T cell immunity; Omicron variant; neutralizing antibody; SARS-CoV-2; spike protein; mRNA vaccine

The development of vaccines that can efficiently prevent the infection of SARS-CoV-2 is necessary to fight the COVID-19 epidemic. mRNA vaccine has been proven to induce strong humoral and cellular immunity against SARS-CoV-2. Here, we studied the immunogenicity and protection efficacy of a novel mRN...