Critical periods in Drosophila neural network development: Importance to network tuning and therapeutic potential

• Published in: Frontiers in physiology Vol. 13; p. 1073307
• Main Authors: Coulson, Bramwell, Hunter, Iain, Doran, Sarah, Parkin, Jill, Landgraf, Matthias, Baines, Richard A
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 02.12.2022
• Subjects: critical period; development; Drosophila; homeostasis; network; neuron; Physiology; neuron; homeostasis; development; critical period; Drosophila; network

Critical periods are phases of heightened plasticity that occur during the development of neural networks. Beginning with pioneering work of Hubel and Wiesel, which identified a critical period for the formation of ocular dominance in mammalian visual network connectivity, critical periods have been...