Gender differences in long-term beneficial effects of erythropoietin given after neonatal stroke in postnatal day-7 rats

• Published in: Neuroscience Vol. 139; no. 3; pp. 803 - 811
• Main Authors: Wen, T.C., Rogido, M., Peng, H., Genetta, T., Moore, J., Sola, A.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 2006
• Subjects: Animals; Animals, Newborn; Brain - drug effects; Brain - growth & development; erythropoietin; Erythropoietin - therapeutic use; Female; gender differences; Humans; Male; neonatal focal stroke; neuroprotection; Neuroprotective Agents - therapeutic use; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sex Factors; Stroke - drug therapy; CCA; HI; ECA; Epo; ICA; MCA; FCI; gender differences; neonatal focal stroke; P; neuroprotection; SO; erythropoietin
• ISSN: 0306-4522; 1873-7544
• DOI: 10.1016/j.neuroscience.2006.02.057

Recently, we reported that erythropoietin attenuates neonatal brain injury caused by focal cerebral ischemia. The long-term effects of erythropoietin on focal cerebral ischemia-induced injury to the developing brain and the potential gender differences in these long-term effects have not been studie...