Immune activation of characteristic gut mycobiota Kazachstania pintolopesii on IL-23/IL-17R signaling in ankylosing spondylitis

• Published in: Frontiers in cellular and infection microbiology Vol. 12; p. 1035366
• Main Authors: Zhang, Haiting, Wei, Yu, Jia, Huanhuan, Chen, Diling, Tang, Xiaocui, Wang, Jian, Chen, Meili, Guo, Yinrui
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 20.12.2022
• Subjects: Animals; ankylosing spondylitis; autoimmune response; Bacteria; Cellular and Infection Microbiology; communication/interaction network; Dysbiosis - microbiology; fungal and bacterial dysbiosis; Gastrointestinal Microbiome; Interleukin-23; Kazachstania pintolopesii; Mice; Mice, Inbred C57BL; RNA, Ribosomal, 16S - genetics; Saccharomycetales - genetics; Spondylitis, Ankylosing; autoimmune response; communication/interaction network; fungal and bacterial dysbiosis; Kazachstania pintolopesii; ankylosing spondylitis

It is very important to understand the communication and interaction mechanisms between the host and its resident microorganisms on host physiology and for precise diagnosis and treatment. Although intestinal fungi and bacteria dysbiosis is increasingly linked to ankylosing spondylitis (AS), their m...