A CEACAM6-High Airway Neutrophil Phenotype and CEACAM6-High Epithelial Cells Are Features of Severe Asthma - Shikotra, Aarti; Choy, David F; Siddiqui, Salman; Arthur, Greer; Nagarkar, Deepti R; Jia, Guiquan; Wright, Adam K A; Ohri, Chandra M; Doran, Emma; Butler, Claire A; Hargadon, Beverley; Abbas, Alexander R; et al. (The Journal of immunology (1950), 2017)
Keywords: Adult; Antigens, CD - immunology; Asthma; Asthma - immunology; Biopsy; Bronchus; Cell adhesion & migration; Cell adhesion molecules; Cell Adhesion Molecules - immunology; Corticosteroids; DNA microarrays; Elastase; Enzyme-Linked Immunosorbent Assay; Epithelial cells; Epithelial Cells - immunology; Female; Flow Cytometry; Fluorescent Antibody Technique; Gene expression; Gene Expression Profiling; GPI-Linked Proteins - immunology; Helper cells; Humans; Immunohistochemistry; Inflammation; Lamina propria; Leukocytes (neutrophilic); Localization; Lymphocytes T; Male; Middle Aged; Mucosa; Neutrophils; Neutrophils - immunology; Phenotype; Polymerase Chain Reaction; Respiratory Mucosa - immunology; Respiratory tract; Transcriptome; Wounding