One-step synthesis of potassium ferricyanide-doped polyaniline nanoparticles for label-free immunosensor

• Published in: Biosensors & bioelectronics Vol. 68; pp. 462 - 467
• Main Authors: He, Sijing, Wang, Qiyou, Yu, Yanyan, Shi, Qiujia, Zhang, Lin, Chen, Zuanguang
• Format: Journal Article
• Language: English
• Published: England 15.06.2015
• Subjects: adsorption; aniline; Aniline Compounds - chemical synthesis; Aniline Compounds - chemistry; Antibodies; Antibodies - chemistry; Antibodies - immunology; Antigens; Biosensing Techniques; Carcinoembryonic Antigen - chemistry; Carcinoembryonic Antigen - immunology; Carcinoembryonic Antigen - isolation & purification; Charging; Chitosan - chemistry; detection limit; electrodes; Ferricyanides - chemical synthesis; Ferricyanides - chemistry; Gold; Gold - chemistry; Humans; Immunoassay - methods; immunoassays; Immunosensors; Limit of Detection; Metal Nanoparticles - chemistry; nanogold; Nanoparticles; oxidants; Polyanilines; polymerization; Surface chemistry; Carcinoembryonic antigen; Label-free immunosensor; Potassium ferricyanide-doped polyaniline nanoparticles; Gold nanoparticles; One-step synthesis

A novel, label-free and inherent electroactive redox immunosensor for ultrasensitive detection of carcinoembryonic antigen (CEA) was proposed based on gold nanoparticles (AuNPs) and potassium ferricyanide-doped polyaniline (FC-PANI) nanoparticles. FC-PANI composite was synthesized via oxidative poly...