The effects of RNA editing in cancer tissue at different stages in carcinogenesis

• Published in: RNA biology Vol. 18; no. 11; pp. 1524 - 1539
• Main Authors: Kurkowiak, Małgorzata, Arcimowicz, Łukasz, Chruściel, Elżbieta, Urban-Wójciuk, Zuzanna, Papak, Ines, Keegan, Liam, O'Connell, Mary, Kowalski, Jacek, Hupp, Ted, Marek-Trzonkowska, Natalia
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 02.11.2021
• Subjects: ADARs; Adenosine - genetics; Animals; cancer development; Carcinogenesis - genetics; Carcinogenesis - pathology; Humans; Inosine - genetics; Neoplasms - genetics; Neoplasms - metabolism; Neoplasms - pathology; Review; RNA Editing; RNA editing in cancer; RNA, Double-Stranded - genetics; RNA-Binding Proteins - genetics; RNA-Binding Proteins - metabolism; RNA editing; RNA editing in cancer; ADARs; cancer development

RNA editing is one of the most prevalent and abundant forms of post-transcriptional RNA modification observed in normal physiological processes and often aberrant in diseases including cancer. RNA editing changes the sequences of mRNAs, making them different from the source DNA sequence. Edited mRNA...