The Unique Phylogenetic Position of a Novel Tick-Borne Phlebovirus Ensures an Ixodid Origin of the Genus Phlebovirus

• Published in: mSphere Vol. 3; no. 3
• Main Authors: Matsuno, Keita, Kajihara, Masahiro, Nakao, Ryo, Nao, Naganori, Mori-Kajihara, Akina, Muramatsu, Mieko, Qiu, Yongjin, Torii, Shiho, Igarashi, Manabu, Kasajima, Nodoka, Mizuma, Keita, Yoshii, Kentaro, Sawa, Hirofumi, Sugimoto, Chihiro, Takada, Ayato, Ebihara, Hideki
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 27.06.2018
• Subjects: Arachnids; Arthropods; Coccidioidomycosis; Collaboration; Coronary artery disease; Epidemiology; Evolution; Fever; Genomes; Heart diseases; Infectious diseases; Interferon; Ixodes persulcatus; Laboratories; Microscopy; Mosquitoes; Phenuiviridae; Phylogenetics; Phylogeny; Public health; Research centers; Rift Valley fever; RNA viruses; Thrombocytopenia; Tick-borne diseases; Vectors; Veterinary medicine; Viruses; West Nile virus; Zoonoses; United States > US; Japan; Zambia; tick-borne phlebovirus; ancestral state; phylogenetic analysis; evolution

The emergence of novel tick-borne RNA viruses causing severe illness in humans has complicated the epidemiological landscape of tick-borne diseases, requiring further investigation to safeguard public health. In the present study, we discovered a novel tick-borne phlebovirus from Ixodes persulcatus...