TLR7 agonism accelerates disease in a mouse model of primary Sjögren’s syndrome and drives expansion of T-bet+ B cells - Punnanitinont, Achamaporn; Kasperek, Eileen M.; Kiripolsky, Jeremy; Zhu, Chengsong; Miecznikowski, Jeffrey C.; Kramer, Jill M. (Frontiers in immunology, 2022)
Keywords: ABC; Adjuvants, Immunologic - pharmacology; age-associated B cells; Animals; autoantibodies; autoimmunity; B-Lymphocytes - drug effects; B-Lymphocytes - immunology; Female; Imiquimod - pharmacology; Immunology; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Myeloid Differentiation Factor 88 - genetics; Myeloid Differentiation Factor 88 - immunology; NOD.B10; sialadenitis; Sjogren's Syndrome - genetics; Sjogren's Syndrome - immunology; Toll-Like Receptor 7 - agonists; Toll-Like Receptor 7 - genetics; Toll-Like Receptor 7 - immunology; ABC; autoimmunity; sialadenitis; autoantibodies; age-associated B cells; NOD.B10