In Vivo F-Actin Filament Organization during Lymphocyte Transendothelial and Interstitial Migration Revealed by Intravital Microscopy

• Published in: iScience Vol. 16; pp. 283 - 297
• Main Authors: Yan, Serena L.S., Hwang, Il-Young, Kamenyeva, Olena, Kehrl, John H.
• Format: Journal Article
• Language: English
• Published: United States Elsevier 28.06.2019
• Subjects: Biological Sciences; Organizational Aspects of Cell Biology; Cell Biology

Actin is essential for many cellular processes including cell motility. Yet the organization of F-actin filaments during lymphocyte transendothelial migration (TEM) and interstitial migration have not been visualized. Here we report a high-resolution confocal intravital imaging technique with LifeAc...