Is methamphetamine use associated with idiopathic pulmonary arterial hypertension?

• Published in: Chest Vol. 130; no. 6; p. 1657
• Main Authors: Chin, Kelly M, Channick, Richard N, Rubin, Lewis J
• Format: Journal Article
• Language: English
• Published: United States 01.12.2006
• Subjects: Adult; Amphetamine - toxicity; California; Central Nervous System Stimulants - toxicity; Chronic Disease; Cocaine - toxicity; Drug Interactions; Female; Humans; Hypertension, Pulmonary - chemically induced; Hypertension, Pulmonary - diagnosis; Hypertension, Pulmonary - epidemiology; Likelihood Functions; Logistic Models; Male; Methamphetamine - toxicity; Middle Aged; Pulmonary Embolism - complications; Pulmonary Embolism - diagnosis; Pulmonary Embolism - epidemiology; Retrospective Studies; Risk Factors; Street Drugs - toxicity; Substance Abuse, Intravenous - complications; Substance Abuse, Intravenous - diagnosis; Substance Abuse, Intravenous - epidemiology; California

Amphetamine, methamphetamine, and cocaine are suspected of being pulmonary hypertension risk factors based on a small number of case reports along with pharmacologic similarities to fenfluramine, a diet drug associated with pulmonary arterial hypertension (PAH). We sought to determine whether rates...