Injectable Peptide Hydrogel Enables Integrated Tandem Enzymes' Superactivity for Cancer Therapy

• Published in: iScience Vol. 14; pp. 27 - 35
• Main Authors: Wei, Qingcong, Jiang, Shan, Zhu, Rongrong, Wang, Xia, Wang, Shilong, Wang, Qigang
• Format: Journal Article
• Language: English
• Published: United States Elsevier 26.04.2019
• Subjects: Biological Sciences; Medical Biochemistry; Cancer

Elevation of the levels of reactive oxygen species and other toxic radicals is an emerging strategy to treat certain cancers by modulating the redox status of cancer cells. The biocatalytic upregulation of singlet oxygen by neutrophilic leukocytes should utilize robust enzymes and design carriers wi...