Effects of gradient non-linearity correction and intensity non-uniformity correction in longitudinal studies using structural image evaluation using normalization of atrophy (SIENA)

• Published in: Journal of magnetic resonance imaging Vol. 32; no. 2; pp. 489 - 492
• Main Authors: Takao, Hidemasa, Abe, Osamu, Hayashi, Naoto, Kabasawa, Hiroyuki, Ohtomo, Kuni
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.08.2010
• Subjects: Adult; Aged; Aged, 80 and over; Atrophy - pathology; Brain - pathology; Brain Mapping; brain volume; Female; gradient non-linearity; Humans; Image Processing, Computer-Assisted - methods; intensity non-uniformity; Longitudinal Studies; longitudinal study; Magnetic Resonance Imaging - methods; Male; Middle Aged; SIENA; Software
• ISSN: 1053-1807; 1522-2586; 1522-2586
• DOI: 10.1002/jmri.22237

Purpose: To evaluate the effects of gradient nonlinearity correction and intensity nonuniformity correction on longitudinal (two‐year) changes in global and regional brain volumes. Materials and Methods: A total of 208 subjects (70 females and 138 males, age range = 38.1–83.0 years) were included in...