Exercise-Induced Cardiac Troponin Elevations: From Underlying Mechanisms to Clinical Relevance

• Published in: Circulation (New York, N.Y.) Vol. 144; no. 24; pp. 1955 - 1972
• Main Authors: Aengevaeren, Vincent L., Baggish, Aaron L., Chung, Eugene H., George, Keith, Kleiven, Øyunn, Mingels, Alma M.A., Ørn, Stein, Shave, Rob E., Thompson, Paul D., Eijsvogels, Thijs M.H.
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 14.12.2021
• Subjects: Cardiovascular Diseases - metabolism; Exercise; Humans; Kinetics; State of the Art; Troponin - metabolism; apoptosis; cardiomegaly, exercise-induced; athletes; necrosis; heart; heart injuries

Serological assessment of cardiac troponins (cTn) is the gold standard to assess myocardial injury in clinical practice. A greater magnitude of acutely or chronically elevated cTn concentrations is associated with lower event-free survival in patients and the general population. Exercise training is...