Automatic Bone Marrow Cellularity Estimation in H&E Stained Whole Slide Images

• Published in: Cytometry. Part A Vol. 95; no. 10; pp. 1066 - 1074
• Main Authors: Nielsen, Frederik Skou, Pedersen, Mads Jozwiak, Olsen, Mathias Vassard, Larsen, Morten Skaarup, Røge, Rasmus, Jørgensen, Alex Skovsbo
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.10.2019; Wiley Subscription Services, Inc
• Subjects: Algorithms; Annotations; Automation; Biopsy; Bone marrow; Cellularity; Classification; Correlation coefficient; Correlation coefficients; Cytometry; Diagnostic systems; Estimates; Ground truth; Image processing; Image segmentation; Inspection; Segmentation; WSI H&E stains; Bone marrow; Segmentation; WSI H&E stains; Cellularity; Classification

Bone marrow cellularity is an important measure in diagnostic hematopathology. Currently, the gold standard for bone marrow cellularity estimation is manual inspection of hematoxylin and eosin stained whole slide images (H&E WSI) by hematopathologists. However, these assessments are subjective a...