Morita–Baylis–Hillman (MBH) Reaction Derived Nitroallylic Alcohols, Acetates and Amines as Synthons in Organocatalysis and Heterocycle Synthesis

• Published in: Chemical record Vol. 17; no. 3; pp. 363 - 381
• Main Authors: Huang, Wan‐Yun, Anwar, Shaik, Chen, Kwunmin
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.03.2017
• Subjects: Alcohol; asymmetric synthesis; heterocycles; nitroallylic alcohols; organocatalysis; sequential reaction; organocatalysis; nitroallylic alcohols; sequential reaction; asymmetric synthesis; heterocycles

The Morita–Baylis–Hillman (MBH) reaction is one of the most useful and efficient protocols for constructing new carbon–carbon bonds between an activated olefin and electrophiles in the presence of a tertiary amine/phosphine. Herein, we present the use of MBH alcohols, which are obtained from the rea...