Tricepyridinium‐inspired QACs yield potent antimicrobials and provide insight into QAC resistance - Garrison, Michelle A.; Mahoney, Andrew R.; Wuest, William M. (ChemMedChem, 2021)
Keywords: Alkyl compounds; Ammonium; ammonium compound; Ammonium compounds; Analogs; Anti-Bacterial Agents - chemical synthesis; Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - pharmacology; Antibacterial; Antimicrobial agents; antiseptic; Benzalkonium chloride; Biological analysis; Cetylpyridinium chloride; Chemistry, Medicinal; Chlorides; Consumer products; Disinfectants; Dose-Response Relationship, Drug; Drug resistance; Escherichia coli - drug effects; Indoles - chemistry; Indoles - pharmacology; Liability; Life Sciences & Biomedicine; Microbial Sensitivity Tests; Models, Molecular; Molecular modelling; Molecular Structure; MRSA; natural product; Natural products; Pharmacology & Pharmacy; Pseudomonas aeruginosa - drug effects; Pyridinium Compounds - chemistry; Pyridinium Compounds - pharmacology; Quaternary ammonium compounds; Quaternary Ammonium Compounds - chemistry; Quaternary Ammonium Compounds - pharmacology; Quaternary ammonium salts; Science & Technology; Selectivity; Staphylococcus - drug effects; Structure-Activity Relationship; antiseptic; ammonium compound; INFECTIONS; DISINFECTANTS; natural product; MRSA; Antibacterial