A Genetic Code Expansion‐Derived Molecular Beacon for the Detection of Intracellular Amyloid‐β Peptide Generation - Sappakhaw, Khomkrit; Jantarug, Krittapas; Slavoff, Sarah A.; Israsena, Nipan; Uttamapinant, Chayasith (Angewandte Chemie International Edition, 2021)
Keywords: Alzheimer's disease; Amino Acyl-tRNA Synthetases - genetics; Amino Acyl-tRNA Synthetases - metabolism; Amyloid beta-Peptides - chemistry; Amyloid beta-Peptides - metabolism; Amyloid beta-Protein Precursor - genetics; Amyloid beta-Protein Precursor - metabolism; Amyloid precursor protein; amyloids; Archaeal Proteins - genetics; Archaeal Proteins - metabolism; Communication; Communications; Genetic Code; genetic code expansion; HEK293 Cells; Humans; Labeling; Lysine - analogs & derivatives; Lysine - chemistry; Lysine - metabolism; Methanosarcina - enzymology; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Neurodegenerative diseases; Pathogenesis; Peptides; Polypeptides; Precursors; Protein Processing, Post-Translational; Proteins; proteoforms; Proteolysis; proteolytic processing; β-Amyloid; amyloids; proteoforms; genetic code expansion; proteolytic processing