Nucleus‐Targeted Organoiridium–Albumin Conjugate for Photodynamic Cancer Therapy - Zhang, Pingyu; Huang, Huaiyi; Banerjee, Samya; Clarkson, Guy J.; Ge, Chen; Imberti, Cinzia; Sadler, Peter J. (Angewandte Chemie International Edition, 2019)
Keywords: A549 Cells; Albumin; Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacology; Cancer; Cancer therapies; Cell Nucleus - drug effects; Cell Proliferation - drug effects; Chemical synthesis; Communication; Communications; Coordination Complexes - chemistry; Coordination Complexes - pharmacology; Cytotoxicity; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Human serum albumin; Humans; Iridium - chemistry; Iridium - pharmacology; Irradiation; Models, Molecular; Molecular Structure; Nuclei (cytology); Optical Imaging; organoiridium; Phosphorescence; Photochemotherapy; Photodynamic therapy; photosensitizers; Photosensitizing Agents - chemistry; Photosensitizing Agents - pharmacology; Radiation; Serum albumin; Serum Albumin, Human - chemistry; Serum Albumin, Human - metabolism; Spheroids; Structure-Activity Relationship; Toxicity; Tumor cell lines; photosensitizers; organoiridium; photodynamic therapy; albumin