Profiling of phospholipid molecular species in human breast milk of Chinese mothers and comprehensive analysis of phospholipidomic characteristics at different lactation stages

• Published in: Food chemistry Vol. 348; p. 129091
• Main Authors: Song, Shuang, Liu, Ting-Ting, Liang, Xue, Liu, Zhao-Yan, Yishake, Dinuerguli, Lu, Xiao-Ting, Yang, Meng-Tao, Man, Qing-Qing, Zhang, Jian, Zhu, Hui-Lian
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 30.06.2021
• Subjects: Animals; breast milk; China; digestion; Female; food chemistry; Human milk; Humans; Infant; infant development; Lactation; Lactation period; LC–MS; Lipidomics; lysophosphatidylcholine; milk; Milk, Human - chemistry; Mothers; phosphatidylethanolamines; phosphatidylglycerols; phosphatidylinositols; phosphatidylserines; Phospholipid; Phospholipids - analysis; quantitative analysis; sphingomyelins; China; LPE; LPG; PS; LPI; Phospholipid; MRM; LPL; PU-PL; LPS; SM; MFGM; HILIC-ESI-IT-TOF-MS; WHO; pPC; pPE; EMM; pLPE; PUFA; LC–MS; OPLS-DA; CM; LMM; Lactation period; PCA; PA; PMM; PC; PE; PG; Human milk; PI; TM; HILIC-ESI-MS/MS; pLPC; PL; LPA; LPC

•Precise qualitative and quantitative analysis of phospholipid molecular species.•258 phospholipid molecular species were characterized in 486 human milk samples.•Dynamic changes of classes and sub classes of phospholipid over time were analyzed.•Critical change of phospholipid profile between lacta...