Plasmon-enhanced fluorescence spectroscopy

Fluorescence spectroscopy with strong emitters is a remarkable tool with ultra-high sensitivity for detection and imaging down to the single-molecule level. Plasmon-enhanced fluorescence (PEF) not only offers enhanced emissions and decreased lifetimes, but also allows an expansion of the field of fl...

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Bibliographic Details
Published inChemical Society reviews Vol. 46; no. 13; pp. 3962 - 3979
Main Authors Li, Jian-Feng, Li, Chao-Yu, Aroca, Ricardo F
Format Journal Article
LanguageEnglish
Published England 03.07.2017
Subjects
Coupling (molecular)
detection limit
emissions
Emitters
Fluorescence
fluorescence emission spectroscopy
fluorescent dyes
image analysis
Imaging
nanoparticles
Nanostructure
photobleaching
Plasmons
Sensitivity
Spectroscopy
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Summary:Fluorescence spectroscopy with strong emitters is a remarkable tool with ultra-high sensitivity for detection and imaging down to the single-molecule level. Plasmon-enhanced fluorescence (PEF) not only offers enhanced emissions and decreased lifetimes, but also allows an expansion of the field of fluorescence by incorporating weak quantum emitters, avoiding photobleaching and providing the opportunity of imaging with resolutions significantly better than the diffraction limit. It also opens the window to a new class of photostable probes by combining metal nanostructures and quantum emitters. In particular, the shell-isolated nanostructure-enhanced fluorescence, an innovative new mode for plasmon-enhanced surface analysis, is included. These new developments are based on the coupling of the fluorophores in their excited states with localized surface plasmons in nanoparticles, where local field enhancement leads to improved brightness of molecular emission and higher detection sensitivity. Here, we review the recent progress in PEF with an emphasis on the mechanism of plasmon enhancement, substrate preparation, and some advanced applications, including an outlook on PEF with high time- and spatially resolved properties. Fluorescence spectroscopy with strong emitters is a remarkable tool with ultra-high sensitivity for detection and imaging down to the single-molecule level.
Bibliography:Jian-Feng Li is a Professor of Chemistry at Xiamen University. He received a BSc in chemistry from Zhejiang University, and a PhD in chemistry from Xiamen University. Professor Li is the principal inventor of shell-isolated nanoparticle-enhanced Raman spectroscopy (SHINERS). His research interests include surface-enhanced Raman spectroscopy, surface-enhanced fluorescence, core-shell nanostructures, surface plasmon resonance, electrochemistry and surface catalysis.
Chao-Yu Li is now pursuing his PhD degree under the supervision of Prof. Zhong-Qun Tian and Prof. Jian-Feng Li at Xiamen University. His research is focused on spectroelectrochemistry, synthesis of plasmonic nanostructures, and plasmon-enhanced single-molecule spectroscopy.
Dr Ricardo Aroca is Professor Emeritus in the Department of Chemistry and Biochemistry at the University of Windsor, and Adjunct Professor in the Department of Chemistry, Faculty of Science, University of Chile. In 2003 he was honoured with the Gerhard Herzberg Award in recognition of outstanding achievement in the science of spectroscopy. In 2005 he was elected Fellow of the Chemical Institute of Canada. Since 2009, he has also been a Member Correspondent of the Chilean Academy of Sciences. His research is on plasmon enhanced spectroscopy.
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ISSN:0306-0012
1460-4744
1460-4744
DOI:10.1039/c7cs00169j