Research progress on the mechanism of beta-cell apoptosis in type 2 diabetes mellitus

• Published in: Frontiers in Endocrinology Vol. 13; p. 976465
• Main Authors: You, SuFang, Zheng, JingYi, Chen, YuPing, Huang, HuiBin
• Format: Journal Article
• Language: English
• Published: Frontiers Media SA 18.08.2022; Frontiers Media S.A
• Subjects: apoptosis; beta-cell; Diabetes Mellitus, Type 2; Diseases of the endocrine glands. Clinical endocrinology; Endocrinology; exosomes; glucolipotoxicity; Humans; Insulin-Secreting Cells; non-coding RNAs; Pancreas; RC648-665; type 2 diabetes

Type 2 diabetes mellitus(T2DM) is regarded as one of the most severe chronic metabolic diseases worldwide, which poses a great threat to human safety and health. The main feature of T2DM is the deterioration of pancreatic beta-cell function. More and more studies have shown that the decline of pancr...