Skeletal muscle nitric oxide signaling and exercise: a focus on glucose metabolism

• Published in: American journal of physiology: endocrinology and metabolism Vol. 303; no. 3; pp. E301 - E307
• Main Authors: McConell, Glenn K, Rattigan, Stephen, Lee-Young, Robert S, Wadley, Glenn D, Merry, Troy L
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.08.2012
• Subjects: Animals; Biosynthesis; Exercise - physiology; Glucose; Glucose - metabolism; Humans; Insulin resistance; Metabolism; Models, Biological; Muscle Contraction - physiology; Muscle, Skeletal - chemistry; Muscle, Skeletal - metabolism; Musculoskeletal system; Nitric oxide; Nitric Oxide - metabolism; Nitric Oxide Synthase - metabolism; Physiology; Signal Transduction - physiology

Nitric oxide (NO) is an important vasodilator and regulator in the cardiovascular system, and this link was the subject of a Nobel prize in 1998. However, NO also plays many other regulatory roles, including thrombosis, immune function, neural activity, and gastrointestinal function. Low concentrati...