Role of l- and d-Menthol in the Glucuronidation and Detoxification of the Major Lung Carcinogen, NNAL - Kozlovich, Shannon; Chen, Gang; Watson, Christy J.W.; Blot, William J.; Lazarus, Philip (Drug metabolism and disposition, 2019)
Keywords: 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone; Butanol; Carcinogens; Carcinogens - metabolism; Cigarette smoking; Cigarettes; Cohort Studies; Detoxification; DNA damage; Enantiomers; Flavors; Glucuronides - urine; Glucuronosyltransferase; Glucuronosyltransferase - genetics; Glucuronosyltransferase - metabolism; HEK293 Cells; Humans; Menthol; Menthol - metabolism; Menthol - urine; Metabolic pathways; Metabolites; Microsomes; Microsomes, Liver - metabolism; Nitrogen; Nitrosamines - metabolism; Nitrosamines - urine; Pyridines; Smoking; Smoking - metabolism; Smoking - urine; Stereoisomerism; Tobacco; Tobacco Products; Transfection; UDP-glucuronosyltransferase; Urine; UGT; MS; SCCS; HLM; IS; NNK; HIM; NNAL; LC-MS/MS; HEK293; TSNA; UPLC; MG; QTOF