The SOS-LUX-TOXICITY-Test on the International Space Station

• Published in: Research in microbiology Vol. 157; no. 1; pp. 30 - 36
• Main Authors: Rabbow, Elke, Stojicic, Nevena, Walrafen, David, Baumstark-Khan, Christa, Rettberg, Petra, Schulze-Varnholt, Dirk, Franz, Markus, Reitz, Günther
• Format: Journal Article
• Language: English
• Published: Paris Elsevier SAS 2006; Elsevier
• Subjects: Bacteriological Techniques; Bioassay; Biological and medical sciences; Bioluminescence; Biosensing Techniques; Cosmic Radiation - adverse effects; DNA Repair; DNA, Bacterial - genetics; Fundamental and applied biological sciences. Psychology; Genome, Bacterial; Genotoxicity; Green fluorescent protein; Life Support Systems; Luminescent Measurements; Microbiology; Mutagenicity Tests; Operon; Photobacterium - genetics; Photobacterium leiognathi; Plasmids; Promoter Regions, Genetic; Radiation; Salmonella typhimurium - genetics; Salmonella typhimurium - growth & development; Salmonella typhimurium - radiation effects; SOS Response (Genetics); Space; Space Flight; Spacecraft; Ultraviolet Rays - adverse effects; Weightlessness - adverse effects; Space; Bioluminescence; Bioassay; Green fluorescent protein; Radiation; Genotoxicity; Microbiology; Mutagenicity testing; Toxicity; SOS function

For the safety of astronauts and to ensure the stability and integrity of the genome of microorganisms and plants used in bioregenerative life support systems, it is important to improve our knowledge of the combined action of (space) radiation and microgravity. The SOS-LUX-TOXICITY test, as part of...