Tea saponin additive to extract eleutheroside B and E from Eleutherococcus senticosus by ultrasonic mediation and its application in a semi-pilot scale

•Use ultrasonic-assisted extraction of eleutheroside B and E from E. senticosus.•Tea saponin was first added to extract eleutherosides in the process.•Dynamic models under powers, temperatures were considered.•Determine optimum conditions of eleutheroside B and E by response surface method.•A 200-fo...

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Published inUltrasonics sonochemistry Vol. 86; p. 106039
Main Authors Yang, Xinyu, Liu, Tingting, Qi, Shuwen, Gu, Huiyan, Li, Jialei, Yang, Lei
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.05.2022
Elsevier
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ISSN1350-4177
1873-2828
1873-2828
DOI10.1016/j.ultsonch.2022.106039

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Abstract •Use ultrasonic-assisted extraction of eleutheroside B and E from E. senticosus.•Tea saponin was first added to extract eleutherosides in the process.•Dynamic models under powers, temperatures were considered.•Determine optimum conditions of eleutheroside B and E by response surface method.•A 200-fold expansion of the semi-pilot test was carried out. The safety of ethanol in operations and its effects on human health are gradually being questioned. Under this premise, we attempted to use the natural surfactant tea saponin, which originates from the processing residues of camellia oil, as the additive of the extraction solvent and to extract eleutheroside B and eleutheroside E in the roots and rhizomes of E. senticosus by ultrasonic mediation. After a single-factor experiment, extraction kinetics at different powers and reaction temperatures, and Box–Behnken design optimization, the optimal conditions obtained were 0.3% tea saponin solution as the extraction solvent, 20 mL/g liquid–solid ratio, 250 W ultrasonic irradiation power (43.4 mW/g ultrasonic power density) and 40 min ultrasonic irradiation time. Under optimal conditions, satisfactory yields of eleutheroside B (1.06 ± 0.04 mg/g) and eleutheroside E (2.65 ± 0.12 mg/g) were obtained with semi pilot scale ultrasonic extraction equipment. The experiments showed that compared with the traditional thermal extraction process, the extraction time is significantly reduced at lower operating temperatures.
AbstractList The safety of ethanol in operations and its effects on human health are gradually being questioned. Under this premise, we attempted to use the natural surfactant tea saponin, which originates from the processing residues of camellia oil, as the additive of the extraction solvent and to extract eleutheroside B and eleutheroside E in the roots and rhizomes of E. senticosus by ultrasonic mediation. After a single-factor experiment, extraction kinetics at different powers and reaction temperatures, and Box–Behnken design optimization, the optimal conditions obtained were 0.3% tea saponin solution as the extraction solvent, 20 mL/g liquid–solid ratio, 250 W ultrasonic irradiation power (43.4 mW/g ultrasonic power density) and 40 min ultrasonic irradiation time. Under optimal conditions, satisfactory yields of eleutheroside B (1.06 ± 0.04 mg/g) and eleutheroside E (2.65 ± 0.12 mg/g) were obtained with semi pilot scale ultrasonic extraction equipment. The experiments showed that compared with the traditional thermal extraction process, the extraction time is significantly reduced at lower operating temperatures.
• Use ultrasonic-assisted extraction of eleutheroside B and E from E. senticosus. • Tea saponin was first added to extract eleutherosides in the process. • Dynamic models under powers, temperatures were considered. • Determine optimum conditions of eleutheroside B and E by response surface method. • A 200-fold expansion of the semi-pilot test was carried out. The safety of ethanol in operations and its effects on human health are gradually being questioned. Under this premise, we attempted to use the natural surfactant tea saponin, which originates from the processing residues of camellia oil, as the additive of the extraction solvent and to extract eleutheroside B and eleutheroside E in the roots and rhizomes of E. senticosus by ultrasonic mediation. After a single-factor experiment, extraction kinetics at different powers and reaction temperatures, and Box–Behnken design optimization, the optimal conditions obtained were 0.3% tea saponin solution as the extraction solvent, 20 mL/g liquid–solid ratio, 250 W ultrasonic irradiation power (43.4 mW/g ultrasonic power density) and 40 min ultrasonic irradiation time. Under optimal conditions, satisfactory yields of eleutheroside B (1.06 ± 0.04 mg/g) and eleutheroside E (2.65 ± 0.12 mg/g) were obtained with semi pilot scale ultrasonic extraction equipment. The experiments showed that compared with the traditional thermal extraction process, the extraction time is significantly reduced at lower operating temperatures.
The safety of ethanol in operations and its effects on human health are gradually being questioned. Under this premise, we attempted to use the natural surfactant tea saponin, which originates from the processing residues of camellia oil, as the additive of the extraction solvent and to extract eleutheroside B and eleutheroside E in the roots and rhizomes of E. senticosus by ultrasonic mediation. After a single-factor experiment, extraction kinetics at different powers and reaction temperatures, and Box-Behnken design optimization, the optimal conditions obtained were 0.3% tea saponin solution as the extraction solvent, 20 mL/g liquid-solid ratio, 250 W ultrasonic irradiation power (43.4 mW/g ultrasonic power density) and 40 min ultrasonic irradiation time. Under optimal conditions, satisfactory yields of eleutheroside B (1.06 ± 0.04 mg/g) and eleutheroside E (2.65 ± 0.12 mg/g) were obtained with semi pilot scale ultrasonic extraction equipment. The experiments showed that compared with the traditional thermal extraction process, the extraction time is significantly reduced at lower operating temperatures.The safety of ethanol in operations and its effects on human health are gradually being questioned. Under this premise, we attempted to use the natural surfactant tea saponin, which originates from the processing residues of camellia oil, as the additive of the extraction solvent and to extract eleutheroside B and eleutheroside E in the roots and rhizomes of E. senticosus by ultrasonic mediation. After a single-factor experiment, extraction kinetics at different powers and reaction temperatures, and Box-Behnken design optimization, the optimal conditions obtained were 0.3% tea saponin solution as the extraction solvent, 20 mL/g liquid-solid ratio, 250 W ultrasonic irradiation power (43.4 mW/g ultrasonic power density) and 40 min ultrasonic irradiation time. Under optimal conditions, satisfactory yields of eleutheroside B (1.06 ± 0.04 mg/g) and eleutheroside E (2.65 ± 0.12 mg/g) were obtained with semi pilot scale ultrasonic extraction equipment. The experiments showed that compared with the traditional thermal extraction process, the extraction time is significantly reduced at lower operating temperatures.
•Use ultrasonic-assisted extraction of eleutheroside B and E from E. senticosus.•Tea saponin was first added to extract eleutherosides in the process.•Dynamic models under powers, temperatures were considered.•Determine optimum conditions of eleutheroside B and E by response surface method.•A 200-fold expansion of the semi-pilot test was carried out. The safety of ethanol in operations and its effects on human health are gradually being questioned. Under this premise, we attempted to use the natural surfactant tea saponin, which originates from the processing residues of camellia oil, as the additive of the extraction solvent and to extract eleutheroside B and eleutheroside E in the roots and rhizomes of E. senticosus by ultrasonic mediation. After a single-factor experiment, extraction kinetics at different powers and reaction temperatures, and Box–Behnken design optimization, the optimal conditions obtained were 0.3% tea saponin solution as the extraction solvent, 20 mL/g liquid–solid ratio, 250 W ultrasonic irradiation power (43.4 mW/g ultrasonic power density) and 40 min ultrasonic irradiation time. Under optimal conditions, satisfactory yields of eleutheroside B (1.06 ± 0.04 mg/g) and eleutheroside E (2.65 ± 0.12 mg/g) were obtained with semi pilot scale ultrasonic extraction equipment. The experiments showed that compared with the traditional thermal extraction process, the extraction time is significantly reduced at lower operating temperatures.
ArticleNumber 106039
Author Qi, Shuwen
Yang, Xinyu
Li, Jialei
Gu, Huiyan
Yang, Lei
Liu, Tingting
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Keywords Eleutheroside E
Ultrasonic-assisted extraction
Eleutheroside B
Eleutherococcus senticosus
Tea saponin
Language English
License This is an open access article under the CC BY license.
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Snippet •Use ultrasonic-assisted extraction of eleutheroside B and E from E. senticosus.•Tea saponin was first added to extract eleutherosides in the process.•Dynamic...
The safety of ethanol in operations and its effects on human health are gradually being questioned. Under this premise, we attempted to use the natural...
• Use ultrasonic-assisted extraction of eleutheroside B and E from E. senticosus. • Tea saponin was first added to extract eleutherosides in the process. •...
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SubjectTerms Eleutherococcus senticosus
Eleutheroside B
Eleutheroside E
Short Communication
Tea saponin
Ultrasonic-assisted extraction
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Title Tea saponin additive to extract eleutheroside B and E from Eleutherococcus senticosus by ultrasonic mediation and its application in a semi-pilot scale
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