The Cellular Functions of Eosinophils: Collegium Internationale Allergologicum (CIA) Update 2020

• Published in: International archives of allergy and immunology Vol. 181; no. 1; p. 11
• Main Authors: Simon, Hans-Uwe, Yousefi, Shida, Germic, Nina, Arnold, Isabelle C, Haczku, Angela, Karaulov, Alexander V, Simon, Dagmar, Rosenberg, Helene F
• Format: Journal Article
• Language: English
• Published: Switzerland 2020
• Subjects: Animals; Antibody Formation; Eosinophils - immunology; Humans; Hypereosinophilic Syndrome - immunology; Immunity, Cellular; Immunomodulation; Inflammation - immunology; Interleukin-5; Wound Healing; Eosinophil cytolysis; M2 macrophages; Major basic protein; Targeted therapy; Hypereosinophilic syndromes; Eosinophil degranulation; Inflammation; Mast cells; Eosinophil extracellular traps; Interleukin-5; Asthma; Eosinophils

Eosinophils and their secretory mediators play an important role in the pathogenesis of infectious and inflammatory disorders. Although eosinophils are largely evolutionally conserved, their physiologic functions are not well understood. Given the availability of new eosinophil-targeted depletion th...