Gene Expression Analysis of Human Fetal Ovarian Primordial Follicle Formation

• Published in: The journal of clinical endocrinology and metabolism Vol. 94; no. 4; pp. 1427 - 1435
• Main Authors: Fowler, Paul A., Flannigan, Samantha, Mathers, Anna, Gillanders, Kim, Lea, Richard G., Wood, Maureen J., Maheshwari, Abha, Bhattacharya, Siladitya, Collie-Duguid, Elaina S. R., Baker, Paul J., Monteiro, Ana, O'Shaughnessy, Peter J.
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Endocrine Society 01.04.2009
• Subjects: Abortion, Induced; Autoantigens - genetics; Basic Helix-Loop-Helix Transcription Factors - genetics; Biological and medical sciences; Endocrinopathies; Feeding. Feeding behavior; Female; Fetal Development - genetics; Fundamental and applied biological sciences. Psychology; Gene Expression; Humans; Medical sciences; Oocytes - physiology; Ovarian Follicle - physiology; Ovary - physiology; Pregnancy; Pregnancy Trimester, Second; Transcription, Genetic; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Vertebrates: endocrinology; Human; Obesity; Nutrition; Nutrition disorder; Metabolic diseases; Gene expression; Pregnancy; Ovary; Female genital system; Fetus; Ovarian follicle; Formation; Endocrinology; Nutritional status

Context: Primordial follicle formation dictates the maximal potential female reproductive capacity and establishes the ovarian reserve. Currently, little is known about this process in the human. Objective: The aim of the study was to identify genes associated with the onset of human fetal primordia...