Micropatterning of endothelial cells to create a capillary-like network with defined architecture by laser-assisted bioprinting

• Published in: Journal of materials science. Materials in medicine Vol. 30; no. 2; pp. 28 - 12
• Main Authors: Kérourédan, Olivia, Bourget, Jean-Michel, Rémy, Murielle, Crauste-Manciet, Sylvie, Kalisky, Jérôme, Catros, Sylvain, Thébaud, Noëlie B., Devillard, Raphaël
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.02.2019; Springer Nature B.V; Springer Verlag
• Subjects: Animals; Biocompatible Materials; Biomaterials; Biomedical Engineering and Bioengineering; Biomedical materials; Bioprinting; Bone biomaterials; Cell density; Cell Line; Ceramics; Chemistry and Materials Science; Coculture Techniques; Collagen; Collagen (type I); Collagen - chemistry; Composites; Computer architecture; Density; Endothelial cells; Endothelial Cells - cytology; Glass; Growth factors; Human Umbilical Vein Endothelial Cells - cytology; Humans; Hydrogels; Hydrogels - chemistry; In vivo methods and tests; Infant, Newborn; Lasers; Life Sciences; Materials Science; Mesenchyme; Mice; Micropatterning; Microvasculature; Molar; Natural Materials; Nitric oxide; Polymer Sciences; Printing, Three-Dimensional; Regenerative Medicine/Tissue Engineering; S.I.: Biofabrication and Bioinks for Tissue Engineering; Stem cells; Substitute bone; Surfaces and Interfaces; Surgical implants; Thin Films; Three dimensional printing; Tissue engineering; Tissue Engineering - methods; Tissue Scaffolds; Vascular endothelial growth factor; Vascular Endothelial Growth Factor A - chemistry

Development of a microvasculature into tissue-engineered bone substitutes represents a current challenge. Seeding of endothelial cells in an appropriate environment can give rise to a capillary-like network to enhance prevascularization of bone substitutes. Advances in biofabrication techniques, suc...